Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CASP1 | P29466 | 2/20 | 0.41 |
| ▸ | CASP7 | P55210 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7180542 | 0.84 | PTGS2 (0.67) | PTGS2CYP11B1CYP11B2GPR84BCHE | |
| SCHEMBL29672905 | 0.84 | PTGS2 (0.67) | PTGS2CYP11B1CYP11B2GPR84BCHE | |
| SCHEMBL6287678 | 0.84 | PTGS2 (0.54) | PTGS2ALDH1A1HSD17B10TSHRCYP11B1 | |
| SCHEMBL29606538 | 0.82 | PTGS2 (0.65) | PTGS2CYP11B1CYP11B2GPR84BCHE | |
| SCHEMBL7172726 | 0.82 | PTGS2 (0.65) | PTGS2CYP11B1CYP11B2GPR84BCHE | |
| Hydrochloric Acid SCHEMBL29672906 | 0.80 | PTGS2 (0.62) | PTGS2CYP11B1CYP11B2GPR84DRD2 | |
| Hydrochloric Acid SCHEMBL17835934 | 0.80 | PTGS2 (0.62) | PTGS2CYP11B1CYP11B2GPR84DRD2 | |
| SCHEMBL28324752 | 0.80 | PTGS2 (0.43) | PTGS2ALDH1A1HSD17B10TSHRMAPK1 | |
| Hydrochloric Acid SCHEMBL16516153 | 0.79 | PTGS2 (0.61) | PTGS2CYP11B1CYP11B2GPR84DRD2 | |
| Hydrochloric Acid SCHEMBL30769782 | 0.79 | PTGS2 (0.61) | PTGS2CYP11B1CYP11B2GPR84DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180044450-A1 | BRIDGED METALLOCENE COMPLEX FOR OLEFIN POLYMERIZATION | SAUDI BASIC IND CORP (SA) | 2018-02-15 | — | — | US | disclosed |
| US-9815917-B2 | Bridged metallocene complex for olefin polymerization | SAUDI BASIC INDUSTRIES CORPORATION (SA) | 2017-11-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180044450-A1 | BRIDGED METALLOCENE COMPLEX FOR OLEFIN POLYMERIZATION | ZYX, CPNE4, ZC3HAV1L | PTGS2 1759/4885ALDH1A1 3557/4885HSD17B10 2145/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.