Glycinebetaine

Glycinebetaine

SCHEMBL1959136

CCCC(N)(C(=O)O)N(C)C.C[N+](C)(C)CC(=O)[O-]

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

BHMTBHMT2

The experimentally established mechanism targets of Glycinebetaine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
BBOX1 O75936 2/20 0.35
TSHR P16473 1/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
APEX1 P27695 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dodecanoate SCHEMBL20183472 0.88 GPR84 (0.41) TSHRALDH1A1LMNAAPEX1
Stearic Acid SCHEMBL12544816 0.88 GPR84 (0.41) TSHRALDH1A1LMNAAPEX1
Palmitic Acid SCHEMBL12544931 0.88 GPR84 (0.41) TSHRALDH1A1LMNAAPEX1
Myristic Acid SCHEMBL12545069 0.88 GPR84 (0.41) TSHRALDH1A1LMNAAPEX1
Glycinebetaine SCHEMBL10434275 0.87 TSHR (0.33) BBOX1TSHRALDH1A1LMNAAPEX1
Oleic Acid SCHEMBL20183479 0.82 PPARG (0.49) TSHRALDH1A1LMNAAPEX1
Ammonia Solution, Strong SCHEMBL27815682 0.81 MEN1 (0.36) ALDH1A1LMNA
Myristic Acid SCHEMBL21986530 0.77 GPR84 (0.45) TSHRALDH1A1LMNAAPEX1
Palmitic Acid SCHEMBL21986547 0.77 GPR84 (0.45) TSHRALDH1A1LMNAAPEX1
Glycinebetaine SCHEMBL4620992 0.74 CA1 (0.34) BBOX1TSHRALDH1A1LMNAAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2238969-A1 PREPARATION FOR EXTERNAL APPLICATION TO SKIN AND COSMETIC PREPARATION Showa Denko K.K. (JP) 2010-10-13 EP claimed
US-20230257605-A1 COLORED DISPERSION FOR INKJET, INKJET RECORDING INK, AND INKJET RECORDING METHOD NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2023-08-17 US disclosed
EP-4190868-A1 COLORED DISPERSION FOR INKJET, INKJET RECORDING INK, AND INKJET RECORDING METHOD Nippon Kayaku Kabushiki Kaisha (JP) 2023-06-07 EP disclosed
EP-3327064-B1 CURED SILICONE PARTICLES AND COSMETIC INCORPORATING SAME THEREIN DOW TORAY CO LTD (JP) 2020-04-15 EP disclosed
WO-2019188140-A1 LIQUID DETERGENT COMPOSITION ライオン株式会社 2019-10-03 WO disclosed
EP-3327064-A1 CURED SILICONE PARTICLES AND COSMETIC INCORPORATING SAME THEREIN Dow Corning Toray Co., Ltd. (JP) 2018-05-30 EP disclosed
WO-2014092756-A1 CLEANING COMPOSITION FOR METAL ARTICLES PARKER-HANNIFIN CORPORATION (US) 2014-06-19 WO disclosed
EP-2516511-B1 THICKENER OR GELLANT FOR OIL MATERIALS, GEL COMPOSITION COMPRISING SAME, AND METHOD OF PRODUCING COSMETIC MATERIAL OR TOPICAL AGENT DOW CORNING TORAY CO LTD (JP) 2014-01-22 EP disclosed
EP-2585033-A2 COSMETIC AND TOPICAL SKIN PREPARATION COMPRISING HIGHER ALCOHOL-MODIFIED SILICONE Dow Corning Toray Co., Ltd. (JP) 2013-05-01 EP disclosed
EP-2516511-A2 THICKENER OR GELLANT FOR OIL MATERIALS, GEL COMPOSITION COMPRISING SAME, AND METHOD OF PRODUCING COSMETIC MATERIAL OR TOPICAL AGENT Dow Corning Toray Co., Ltd. (JP) 2012-10-31 EP disclosed
EP-2507290-A1 PRODUCTION METHOD OF DEODORIZED POLYOXYALKYLENE-MODIFIED POLYSILOXANE COMPOSITION Dow Corning Toray Co., Ltd. (JP) 2012-10-10 EP disclosed
WO-2011136389-A2 COSMETIC AND TOPICAL SKIN PREPARATION COMPRISING HIGHER ALCOHOL-MODIFIED SILICONE DOW CORNING TORAY CO., LTD. (JP) 2011-11-03 WO disclosed
WO-2011078395-A2 THICKENER OR GELLANT FOR OIL MATERIALS, GEL COMPOSITION COMPRISING SAME, AND METHOD OF PRODUCING COSMETIC MATERIAL OR TOPICAL AGENT DOW CORNING TORAY CO., LTD. (JP) 2011-06-30 WO disclosed
WO-2011068251-A1 PRODUCTION METHOD OF DEODORIZED POLYOXYALKYLENE-MODIFIED POLYSILOXANE COMPOSITION DOW CORNING TORAY CO., LTD. (JP) 2011-06-09 WO disclosed
US-6641804-B1 Resin and a diluent, the resin (T) providing a resin film having at least one resin selected from the group consisting of vinyl resins, polyester resins, polyamide resins, silicone resins, cationic urethane resins, ampholytic urethane resins SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2003-11-04 US disclosed
EP-1068859-A1 HAIR TREATMENT AND METHOD OF TREATING HAIR SANYO CHEMICAL INDUSTRIES, Ltd. (JP) 2001-01-17 EP disclosed
JP-2000005337-A SYNTHETIC SURFACTANT FOAM CHEMICAL FOR TRAINING HATTA SEISAKUSHO:KK 2000-01-11 JP disclosed
EP-0356784-A2 Liquid detergent composition MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1990-03-07 EP disclosed