SCHEMBL1959536

SCHEMBL1959536

Fc1ccc(OCC2CO2)cc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.66
ALDH1A1 P00352 4/20 0.61
TP53 P04637 3/20 0.61
TSHR P16473 3/20 0.61
MAPT P10636 2/20 0.61
HPGD P15428 2/20 0.61
HIF1A Q16665 2/20 0.61
MEN1 O00255 2/20 0.61
KMT2A Q03164 2/20 0.61
PKM P14618 2/20 0.61
CYP1A2 P05177 1/20 0.61
PPARG P37231 1/20 0.61
LMNA P02545 1/20 0.61
GAA P10253 1/20 0.61
CYP3A4 P08684 1/20 0.58
SMN1; SMN2 Q16637 1/20 0.58
GLA P06280 1/20 0.50
DRD4 P21917 2/20 0.49
LTA4H P09960 1/20 0.44
FGFR1 P11362 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2531000 1.00 TDP1 (0.66) TDP1ALDH1A1TP53TSHRMAPT
SCHEMBL2527003 1.00 TDP1 (0.66) TDP1ALDH1A1TP53TSHRMAPT
SCHEMBL11747205 0.94 TDP1 (0.59) TDP1ALDH1A1TP53TSHRMAPT
SCHEMBL30216927 0.90 MAOB (0.56) TDP1ALDH1A1TP53TSHRMAPT
SCHEMBL31042803 0.90 MAOB (0.56) TDP1ALDH1A1TP53TSHRMAPT
SCHEMBL50264 0.89 TDP1 (0.79) TDP1ALDH1A1TP53TSHRMAPT
SCHEMBL20677146 0.89 TDP1 (0.79) TDP1ALDH1A1TP53TSHRMAPT
SCHEMBL21094081 0.89 TDP1 (0.79) TDP1ALDH1A1TP53TSHRMAPT
SCHEMBL31537004 0.84 ALDH1A1 (0.59) TDP1ALDH1A1TP53TSHRMAPT
SCHEMBL2697929 0.84 TDP1 (0.70) TDP1ALDH1A1TP53TSHRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 196 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118103420-A High-temperature slump retaining material and preparation method thereof 科之杰新材料集团有限公司 2024-05-28 CN claimed
CN-117735883-A Sustained-release slump retaining material and preparation method thereof 科之杰新材料集团有限公司 2024-03-22 CN claimed
CN-117720690-A Plastic-retaining regulator and preparation method thereof 科之杰新材料集团河南有限公司 2024-03-19 CN claimed
CN-111094381-B Process for producing thermoplastic polyoxazolidone polymers 科思创德国股份有限公司 2022-03-22 CN claimed
CN-112585186-A Catalyst for synthesizing oxazolidinone 科思创知识产权两合公司 2021-03-30 CN claimed
CN-109370426-A Coating composition and preparation method thereof, coating piece and preparation method thereof, household electrical appliance 广东美的厨房电器制造有限公司 2019-02-22 CN claimed
CN-109321133-A Coating composition and preparation method thereof, coating piece and preparation method thereof, household electrical appliance 广东美的厨房电器制造有限公司 2019-02-12 CN claimed
CN-107207700-A Method for synthesizing polyoxazolidone compound with high stability 科思创德国股份有限公司 2017-09-26 CN claimed
CN-122037009-A Solid catalyst component, catalyst for olefin prepolymerization or polymerization, and method for olefin prepolymerization or polymerization 中国石油化工股份有限公司 2026-05-15 CN disclosed
CN-122037005-A Catalytic composition, catalyst for olefin prepolymerization or polymerization, process for olefin prepolymerization or polymerization 中国石油化工股份有限公司 2026-05-15 CN disclosed
CN-122037006-A Catalyst component for olefin polymerization, catalyst for olefin prepolymerization or polymerization, and method for olefin prepolymerization or polymerization 中国石油化工股份有限公司 2026-05-15 CN disclosed
CN-122037013-A Catalytic component, catalyst for olefin prepolymerization or polymerization, and method for olefin prepolymerization or polymerization 中国石油化工股份有限公司 2026-05-15 CN disclosed
CN-119552109-A MyD88 inhibitor and application thereof 杭州医学院 2025-03-04 CN disclosed
EP-3522877-B1 SMALL MOLECULE AMPK ACTIVATORS UNIV PITTSBURGH COMMONWEALTH SYS HIGHER EDUCATION (US) 2023-12-06 EP disclosed
EP-0042593-B1 ARYLOXY-PROPANOL AMINES, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THESE COMPOUNDS Roche Diagnostics GmbH (DE) 1985-04-03 EP disclosed
US-4438128-A ADRENERGIC BLOCKERS BOEHRINGER MANNHEIM GMBH (DE) 1984-03-20 US disclosed
EP-0102034-A1 Spiro(2H-1,4-benzodioxepin-3(5H)4'-piperidine and 3'-pyrrolidino) compounds, a process for preparing the same and their use as medicaments HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) 1984-03-07 EP disclosed
EP-0042593-A1 Aryloxy-propanol amines, process for their preparation and medicines containing these compounds Roche Diagnostics GmbH (DE) 1981-12-30 EP disclosed
US-4209639-A 13-Thia-prostaglandins AMERICAN CYANAMID COMPANY (US) 1980-06-24 US disclosed
US-3951986-A Novel 2-propanol derivatives and preparation thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1976-04-20 US disclosed