Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 2/20 | 0.39 |
| ▸ | FLT3 | P36888 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 6/20 | 0.38 |
| ▸ | RAB9A | P51151 | 6/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | ACSL1 | P33121 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
| ▸ | PDE1A | P54750 | 1/20 | 0.36 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.36 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.36 |
| ▸ | SLC34A2 | O95436 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19596014 | 0.91 | SLC34A2 (0.38) | KITFLT3NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6000572 | 0.85 | SLC34A2 (0.55) | KITFLT3SLC34A2MAPK1EPHX2 | |
| SCHEMBL15432843 | 0.84 | KMT2A (0.46) | TSHRHTTKMT2AMEN1LMNA | |
| SCHEMBL19580035 | 0.81 | KIT (0.34) | KITFLT3NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6001503 | 0.77 | SLC34A2 (0.44) | SLC34A2EGFR | |
| SCHEMBL19596069 | 0.77 | SLC34A2 (0.41) | KMT2ASLC34A2NR1H4 | |
| SCHEMBL47756 | 0.75 | SLC34A2 (0.44) | PDE4DKMT2ASLC34A2 | |
| SCHEMBL19595860 | 0.74 | SLC34A2 (0.42) | NPC1RAB9ASMN1; SMN2GAAPAX8 | |
| SCHEMBL16804649 | 0.72 | SLC34A2 (0.55) | SLC34A2LMNA | |
| SCHEMBL19595875 | 0.71 | SLC34A2 (0.46) | NPC1RAB9ASMN1; SMN2GAAPAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2590656-B1 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | ARDELYX INC (US) | 2017-11-15 | — | — | EP | disclosed |