Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC34A2 | O95436 | 1/20 | 0.45 |
| ▸ | RAF1 | P04049 | 5/20 | 0.41 |
| ▸ | BRAF | P15056 | 5/20 | 0.41 |
| ▸ | TEK | Q02763 | 6/20 | 0.38 |
| ▸ | IGF1R | P08069 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 5/20 | 0.35 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
| ▸ | DAPK1 | P53355 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | SRPK2 | P78362 | 1/20 | 0.34 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.34 |
| ▸ | SRPK3 | Q9UPE1 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19596294 | 0.91 | SLC34A2 (0.49) | SLC34A2RAF1BRAFTEKIGF1R | |
| SCHEMBL46664 | 0.90 | SLC34A2 (0.49) | SLC34A2RAF1BRAFTEKKDR | |
| SCHEMBL39707 | 0.88 | SLC34A2 (0.58) | SLC34A2RAF1BRAFTEKKDR | |
| SCHEMBL15444399 | 0.87 | SLC34A2 (0.45) | SLC34A2RAF1BRAFTEKIGF1R | |
| SCHEMBL39971 | 0.87 | SLC34A2 (0.59) | SLC34A2RAF1BRAFTEKNPSR1 | |
| SCHEMBL40138 | 0.85 | SLC34A2 (0.42) | SLC34A2RAF1BRAFTEKALDH1A1 | |
| SCHEMBL19595651 | 0.85 | SLC34A2 (0.48) | SLC34A2RAF1BRAFTEKKDR | |
| SCHEMBL40144 | 0.85 | BRAF (0.50) | SLC34A2RAF1BRAFTEKKDR | |
| SCHEMBL46952 | 0.85 | SLC34A2 (0.44) | SLC34A2RAF1BRAFTEKKDR | |
| SCHEMBL39711 | 0.85 | SLC34A2 (0.46) | SLC34A2RAF1BRAFTEKKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2590656-B1 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | ARDELYX INC (US) | 2017-11-15 | — | — | EP | disclosed |