Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC34A2 | O95436 | 1/20 | 0.48 |
| ▸ | BRAF | P15056 | 6/20 | 0.40 |
| ▸ | RAF1 | P04049 | 4/20 | 0.40 |
| ▸ | TEK | Q02763 | 6/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | KDR | P35968 | 4/20 | 0.33 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15444399 | 0.92 | SLC34A2 (0.45) | SLC34A2BRAFRAF1TEKHTR2A | |
| SCHEMBL39971 | 0.90 | SLC34A2 (0.59) | SLC34A2BRAFRAF1TEKKDM4E | |
| SCHEMBL18482710 | 0.90 | SLC34A2 (0.51) | SLC34A2BRAFRAF1KDM4ENPSR1 | |
| SCHEMBL39707 | 0.90 | SLC34A2 (0.58) | SLC34A2BRAFRAF1TEKKDM4E | |
| SCHEMBL46664 | 0.88 | SLC34A2 (0.49) | SLC34A2BRAFRAF1TEKHTR2A | |
| SCHEMBL39711 | 0.87 | SLC34A2 (0.46) | SLC34A2BRAFRAF1TEKKDR | |
| SCHEMBL19596293 | 0.85 | SLC34A2 (0.45) | SLC34A2BRAFRAF1TEKHTR2A | |
| SCHEMBL39717 | 0.85 | SLC34A2 (0.57) | SLC34A2BRAFRAF1KDM4E | |
| SCHEMBL46952 | 0.84 | SLC34A2 (0.44) | SLC34A2BRAFRAF1TEKKDR | |
| SCHEMBL18482331 | 0.84 | BRAF (0.42) | SLC34A2BRAFRAF1TEKKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2590656-B1 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | ARDELYX INC (US) | 2017-11-15 | — | — | EP | disclosed |