Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK7 | P50613 | 5/20 | 0.42 |
| ▸ | CDK9 | P50750 | 8/20 | 0.41 |
| ▸ | CCNT1 | O60563 | 6/20 | 0.41 |
| ▸ | CCNK | O75909 | 2/20 | 0.41 |
| ▸ | CCNH | P51946 | 2/20 | 0.41 |
| ▸ | MNAT1 | P51948 | 2/20 | 0.41 |
| ▸ | CDK12 | Q9NYV4 | 2/20 | 0.41 |
| ▸ | NAMPT | P43490 | 2/20 | 0.36 |
| ▸ | GRM5 | P41594 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | CDK4 | P11802 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | AXL | P30530 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18069788 | 0.88 | CDK7 (0.53) | CDK7CDK9CCNT1CCNKCCNH | |
| SCHEMBL18069797 | 0.81 | CDK7 (0.45) | CDK7CDK9CCNT1CCNKCCNH | |
| SCHEMBL18069762 | 0.80 | CDK7 (0.50) | CDK7CDK9CCNT1CCNKCCNH | |
| SCHEMBL18069775 | 0.79 | CDK7 (0.42) | CDK7CDK9CCNT1CCNKCCNH | |
| SCHEMBL18069767 | 0.79 | CDK7 (0.50) | CDK7CDK9CCNT1CCNKCCNH | |
| SCHEMBL19580253 | 0.78 | CDK9 (0.42) | CDK7CDK9CCNT1CCNKCCNH | |
| SCHEMBL17688424 | 0.78 | CDK9 (0.42) | CDK7CDK9CCNT1CCNKCCNH | |
| SCHEMBL19600349 | 0.77 | CCNT1 (0.49) | CDK9CCNT1CDK4 | |
| SCHEMBL18069752 | 0.76 | CDK7 (0.42) | CDK7CDK9CCNT1CCNKCCNH | |
| SCHEMBL19600316 | 0.76 | CDK7 (0.42) | CDK7CDK9CCNT1CCNKCCNH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170327496-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 (CDK7) | OXFORD FINANCE LLC, AS COLLATERAL AGENT | 2017-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170327496-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 (CDK7) | CDK7, CDK3, CDK9 | CDK7 1/4885CDK9 3/4885CCNT1 33/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.