SCHEMBL1960043

SCHEMBL1960043

Cc1ccc(N(c2ccc(C)cc2)c2ccc(-c3ccc(-c4ccc(Br)cc4)cc3)cc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.59
MAPK1 P28482 1/20 0.42
TSHR P16473 1/20 0.42
MEN1 O00255 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2C19 P33261 1/20 0.39
HTT P42858 1/20 0.39
KMT2A Q03164 1/20 0.39
APP P05067 3/20 0.38
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
MAOB P27338 1/20 0.38
PAX8 Q06710 1/20 0.38
GAA P10253 1/20 0.37
ACHE P22303 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
CYP2A6 P11509 1/20 0.36
AHR P35869 1/20 0.36
KDM4E B2RXH2 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3446113 1.00 ALDH1A1 (0.59) ALDH1A1MAPK1TSHRMEN1CYP1A2
SCHEMBL346046 1.00 ALDH1A1 (0.59) ALDH1A1MAPK1TSHRMEN1CYP1A2
SCHEMBL23714860 0.93 ALDH1A1 (0.68) ALDH1A1MAPK1TSHRMEN1CYP1A2
SCHEMBL3853531 0.93 ALDH1A1 (0.68) ALDH1A1MAPK1TSHRMEN1CYP1A2
SCHEMBL106962 0.93 ALDH1A1 (0.68) ALDH1A1MAPK1TSHRMEN1CYP1A2
SCHEMBL2858875 0.93 ALDH1A1 (0.68) ALDH1A1MAPK1TSHRMEN1CYP1A2
SCHEMBL13990452 0.93 ALDH1A1 (0.68) ALDH1A1MAPK1TSHRMEN1CYP1A2
SCHEMBL13259842 0.92 ALDH1A1 (0.52) ALDH1A1MAPK1TSHRMEN1CYP1A2
SCHEMBL15583743 0.92 ALDH1A1 (0.58) ALDH1A1MAPK1TSHRMEN1CYP1A2
SCHEMBL6744563 0.92 ALDH1A1 (0.52) ALDH1A1MAPK1TSHRMEN1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2668247-B1 PHOTOTHERAPY DEVICES AND METHODS COMPRISING OPTIONALLY SUBSTITUTED TERPHENYL AND QUATERPHENYL COMPOUNDS NITTO DENKO CORP (JP) 2016-12-28 EP disclosed
US-9373797-B2 Compounds for use in light-emitting devices NITTO DENKO CORPORATION (JP) 2016-06-21 US disclosed
US-9373797-B2 Compounds for use in light-emitting devices NITTO DENKO CORPORATION (JP) 2016-06-21 US disclosed
US-9373797-B2 Compounds for use in light-emitting devices NITTO DENKO CORPORATION (JP) 2016-06-21 US disclosed
EP-2655338-B1 BENZOIMIDAZOLE DERIVATIVES FOR USE IN LIGHT-EMITTING DEVICES NITTO DENKO CORP (JP) 2016-02-24 EP disclosed
EP-2655338-B1 BENZOIMIDAZOLE DERIVATIVES FOR USE IN LIGHT-EMITTING DEVICES NITTO DENKO CORP (JP) 2016-02-24 EP disclosed
US-8929978-B2 Phototherapy devices and methods comprising optionally substituted terphenyl and quaterphenyl compounds NITTO DENKO CORPORATION (JP) 2015-01-06 US disclosed
US-8929978-B2 Phototherapy devices and methods comprising optionally substituted terphenyl and quaterphenyl compounds NITTO DENKO CORPORATION (JP) 2015-01-06 US disclosed
US-8929978-B2 Phototherapy devices and methods comprising optionally substituted terphenyl and quaterphenyl compounds NITTO DENKO CORPORATION (JP) 2015-01-06 US disclosed
US-20130146856-A1 COMPOUNDS FOR USE IN LIGHT-EMITTING DEVICES NITTO DENKO CORPORATION (JP) 2013-06-13 US disclosed
US-8426040-B2 Compounds for use in light-emitting devices NITTO DENKO CORPORATION (JP) 2013-04-23 US disclosed
US-8426040-B2 Compounds for use in light-emitting devices NITTO DENKO CORPORATION (JP) 2013-04-23 US disclosed
US-20120197179-A1 PHOTOTHERAPY DEVICES AND METHODS COMPRISING OPTIONALLY SUBSTITUTED TERPHENYL AND QUATERPHENYL COMPOUNDS NITTO DENKO CORPORATION (JP) 2012-08-02 US disclosed
US-20120197179-A1 PHOTOTHERAPY DEVICES AND METHODS COMPRISING OPTIONALLY SUBSTITUTED TERPHENYL AND QUATERPHENYL COMPOUNDS NITTO DENKO CORPORATION (JP) 2012-08-02 US disclosed
US-20120197179-A1 PHOTOTHERAPY DEVICES AND METHODS COMPRISING OPTIONALLY SUBSTITUTED TERPHENYL AND QUATERPHENYL COMPOUNDS NITTO DENKO CORPORATION (JP) 2012-08-02 US disclosed
WO-2012103380-A1 PHOTOTHERAPY DEVICES AND METHODS COMPRISING OPTIONALLY SUBSTITUTED TERPHENYL AND QUATERPHENYL COMPOUNDS NITTO DENKO CORPORATION (JP) 2012-08-02 WO disclosed
WO-2012088294-A1 BENZOIMIDAZOLE DERIVATIVES FOR USE IN LIGHT - EMITTING DEVICES NITTO DENKO CORPORATION (JP) 2012-06-28 WO disclosed
US-20110140093-A1 COMPOUNDS FOR USE IN LIGHT-EMITTING DEVICES NITTO DENKO CORPORATION (JP) 2011-06-16 US disclosed
US-20110140093-A1 COMPOUNDS FOR USE IN LIGHT-EMITTING DEVICES NITTO DENKO CORPORATION (JP) 2011-06-16 US disclosed
US-20110140093-A1 COMPOUNDS FOR USE IN LIGHT-EMITTING DEVICES NITTO DENKO CORPORATION (JP) 2011-06-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110140093-A1 COMPOUNDS FOR USE IN LIGHT-EMITTING DEVICES NR2E3, CYP3A4, UGT1A4 ALDH1A1 94/4885MAPK1 4807/4885TSHR 2612/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.