Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15445359 | 0.89 | ALDH1A1 (0.41) | ALDH1A1CYP3A4KMT2AMEN1MAPT | |
| SCHEMBL11477434 | 0.88 | ALDH1A1 (0.47) | ALDH1A1CYP3A4KMT2AMEN1KDM4E | |
| SCHEMBL11491096 | 0.88 | ALDH1A1 (0.47) | ALDH1A1CYP3A4KMT2AMEN1KDM4E | |
| SCHEMBL11479562 | 0.88 | ALDH1A1 (0.47) | ALDH1A1CYP3A4KMT2AMEN1KDM4E | |
| Bromide SCHEMBL11482043 | 0.86 | ALDH1A1 (0.46) | ALDH1A1CYP3A4KMT2AMEN1KDM4E | |
| Bromide SCHEMBL11476767 | 0.86 | ALDH1A1 (0.46) | ALDH1A1CYP3A4KMT2AMEN1KDM4E | |
| SCHEMBL15499765 | 0.86 | ALDH1A1 (0.56) | ALDH1A1CYP3A4KMT2AMEN1MAPT | |
| SCHEMBL15242393 | 0.84 | SCN5A (0.47) | ALDH1A1CYP3A4KMT2AMEN1MAPT | |
| Alcohol SCHEMBL11482040 | 0.84 | ALDH1A1 (0.44) | ALDH1A1CYP3A4KMT2AMEN1KDM4E | |
| Alcohol SCHEMBL11476757 | 0.84 | ALDH1A1 (0.44) | ALDH1A1CYP3A4KMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023178289-A2 | CAMPTOTHECIN CONJUGATES | SEAGEN INC. (US) | 2023-09-21 | — | — | WO | disclosed |
| US-20230192858-A1 | ANTI-CTLA4 Antibodies, Antibody Fragments, Their Immunoconjugates and Uses Thereof | BIOATLA, INC. (US) | 2023-06-22 | — | — | US | disclosed |
| WO-2022262789-A1 | ANTITUMOR COMPOUND AND USE THEREOF | 明慧医药（杭州）有限公司 | 2022-12-22 | — | — | WO | disclosed |
| US-20180169259-A1 | ANTI-CD79B ANTIBODIES AND IMMUNOCONJUGATES | GENENTECH INC. (US) | 2018-06-21 | — | — | US | disclosed |
| US-20180015179-A1 | ANTI-CD79B ANTIBODIES AND IMMUNOCONJUGATES | GENENTECH, INC. (US) | 2018-01-18 | — | — | US | disclosed |
| US-20170326248-A1 | ANTI-CD22 ANTIBODIES AND IMMUNOCONJUGATES | GENENTECH, INC (US) | 2017-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170326248-A1 | ANTI-CD22 ANTIBODIES AND IMMUNOCONJUGATES | CD22, CD2, CD2BP2 | ALDH1A1 260/4885CYP3A4 2266/4885KMT2A 2029/4885 |
| US-20230192858-A1 | ANTI-CTLA4 Antibodies, Antibody Fragments, Their Immunoconjugates and Uses Thereof | CD274, IGLV6-57, PDCD1LG2 | ALDH1A1 4133/4885CYP3A4 4470/4885KMT2A 3302/4885 |
| US-20180169259-A1 | ANTI-CD79B ANTIBODIES AND IMMUNOCONJUGATES | CD79B, CD99, CD47 | ALDH1A1 2396/4885CYP3A4 4743/4885KMT2A 1293/4885 |
| US-20180015179-A1 | ANTI-CD79B ANTIBODIES AND IMMUNOCONJUGATES | CD79B, CD99, CD47 | ALDH1A1 2396/4885CYP3A4 4743/4885KMT2A 1293/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.