Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 6/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | THRA | P10827 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17549441 | 0.99 | THRB (0.53) | THRBNPC1LMNASMN1; SMN2NFKB1 | |
| SCHEMBL14000686 | 0.96 | THRB (0.45) | THRBNPC1LMNASMN1; SMN2NFKB1 | |
| SCHEMBL22430188 | 0.96 | THRB (0.45) | THRBNPC1LMNASMN1; SMN2NFKB1 | |
| SCHEMBL15855601 | 0.95 | THRB (0.54) | THRBNPC1LMNASMN1; SMN2NFKB1 | |
| SCHEMBL15855640 | 0.95 | THRB (0.54) | THRBNPC1LMNASMN1; SMN2NFKB1 | |
| SCHEMBL15855638 | 0.95 | THRB (0.54) | THRBNPC1LMNASMN1; SMN2NFKB1 | |
| SCHEMBL15855566 | 0.95 | THRB (0.54) | THRBNPC1LMNASMN1; SMN2NFKB1 | |
| SCHEMBL15855568 | 0.95 | THRB (0.54) | THRBNPC1LMNASMN1; SMN2NFKB1 | |
| SCHEMBL13476095 | 0.95 | NPC1 (0.50) | NPC1LMNASMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL15855603 | 0.94 | THRB (0.55) | THRBNPC1LMNASMN1; SMN2NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170329063-A1 | OPTICAL FILM, POLARIZING PLATE, AND IMAGE DISPLAY DEVICE | FUJIFILM CORPORATION (JP) | 2017-11-16 | — | — | US | disclosed |