⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1416084 | 0.92 | — | — | |
| SCHEMBL7146817 | 0.90 | FAAH (0.57) | — | |
| SCHEMBL11322157 | 0.90 | FAAH (0.57) | — | |
| SCHEMBL9759038 | 0.90 | FAAH (0.57) | — | |
| SCHEMBL11316842 | 0.90 | FAAH (0.57) | — | |
| SCHEMBL16458602 | 0.90 | FAAH (0.57) | — | |
| SCHEMBL10656809 | 0.90 | FAAH (0.57) | — | |
| SCHEMBL28178796 | 0.90 | FAAH (0.57) | — | |
| SCHEMBL288323 | 0.83 | — | — | |
| SCHEMBL1289830 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 712 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9187491-B2 | Gambogenic acid derivatives, preparation method and application thereof | NINTH PEOPLE'S HOSPITAL, SCHOOL MEDICINE SHANGHAI JIAO TONG UNIVERSITY (CN) | 2015-11-17 | — | — | US | claimed |
| EP-2805956-A1 | GAMBOGENIC ACID DERIVATIVES, PREPARATION METHOD AND APPLICATION THEREOF | Ninth People's Hospital, School Medicine Shanghai Jiao Tong University (CN) | 2014-11-26 | — | — | EP | claimed |
| US-20140309418-A1 | Gambogenic Acid Derivatives, Preparation Method and Application Thereof | NINTH PEOPLE'S HOSPITAL, SCHOOL MEDICINE SHANGHAI JIAO TONG UNIVERSITY (CN) | 2014-10-16 | — | — | US | claimed |
| EP-2691403-A1 | NEW BORANOPHOSPHATE ANALOGUES OF CYCLIC NUCLEOTIDES | BIOLOG Life Science Institute Forschungslabor Und Biochemica-Vertrieb GmbH (DE) | 2014-02-05 | — | — | EP | claimed |
| WO-2012130829-A1 | NEW BORANOPHOSPHATE ANALOGUES OF CYCLIC NUCLEOTIDES | BIOLOG LIFE SCIENCE INSTITUTE FORSCHUNGSLABOR UND BIOCHEMICA-VERTRIEB GMBH (DE) | 2012-10-04 | — | — | WO | claimed |
| US-7714025-B2 | Modified chalcone compounds as antimitotic agents | ARIZONA BIOMEDICAL RESEARCH COMMISSION (US) | 2010-05-11 | — | — | US | claimed |
| US-20070265317-A1 | MODIFIED CHALCONE COMPOUNDS AS ANTIMITOTIC AGENTS | ARIZONA BIOMEDICAL RESEARCH COMMISSION (US) | 2007-11-15 | — | — | US | claimed |
| US-20070238893-A1 | Asymmetric hydrogenation of acyl enamides | TEVA PHARMACEUTICAL INDUSTRIES LTD (IL) | 2007-10-11 | — | — | US | claimed |
| WO-2007056403-A2 | ASYMMETRIC HYDROGENATION OF ACYL ENAMIDES | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2007-05-18 | — | — | WO | claimed |
| CN-1747749-A | Diagnostic imaging agents with mmp inhibitory activity | GE HEALTHCARE LTD (GB) | 2006-03-15 | — | — | CN | claimed |
| US-20050197338-A1 | Substituted pyrazole urea compounds for the treatment of inflammation | PHARMACIA AND UPJOHN COMPANY LLC | 2005-09-08 | — | — | US | claimed |
| WO-2005037797-A1 | SUBSTITUTED PYRAZOLE UREA COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | PHARMACIA CORPORATION (US) | 2005-04-28 | — | — | WO | claimed |
| EP-0874846-B1 | PURINE DERIVATIVES AND PROCESSES FOR THEIR PREPARATION | NOVARTIS AG (CH) | 2003-04-02 | — | — | EP | claimed |
| EP-0874846-A1 | PURINE DERIVATIVES AND PROCESSES FOR THEIR PREPARATION | Novartis AG (CH) | 1998-11-04 | — | — | EP | claimed |
| WO-1997016452-A1 | PURINE DERIVATIVES AND PROCESSES FOR THEIR PREPARATION | NOVARTIS AG (CH) | 1997-05-09 | — | — | WO | claimed |
| EP-4373493-A1 | BIFUNCTIONAL COMPOUNDS FOR DEGRADING BTK WITH ENHANCED IMID ACTIVITY | Nurix Therapeutics, Inc. (US) | 2024-05-29 | — | — | EP | disclosed |
| EP-4370123-A1 | BIFUNCTIONAL COMPOUNDS FOR DEGRADING BTK WITH DIMINISHED IMID ACTIVITY | Nurix Therapeutics, Inc. (US) | 2024-05-22 | — | — | EP | disclosed |
| EP-0040408-A1 | Beta-lactam compounds and process for production thereof | SANRAKU-OCEAN CO., LTD. (JP) | 1981-11-25 | — | — | EP | disclosed |
| US-4284631-A | 7-Substituted cephem compounds and pharmaceutical antibacterial compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-08-18 | — | — | US | disclosed |
| EP-0007633-A2 | Cephem compounds, processes for their preparation and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-02-06 | — | — | EP | disclosed |