Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14333101 | 0.86 | ALDH1A1 (0.50) | PKMALDH1A1LMNAMAPT | |
| SCHEMBL4806468 | 0.83 | PDGFRB (0.45) | ALDH1A1OPRK1MAPTMAPK1POLB | |
| SCHEMBL31419042 | 0.83 | PDGFRB (0.45) | ALDH1A1OPRK1MAPTMAPK1POLB | |
| SCHEMBL1336270 | 0.82 | MAPK1 (0.45) | PKMALDH1A1LMNAOPRK1MAPT | |
| SCHEMBL18806713 | 0.80 | PDGFRB (0.45) | PKMALDH1A1OPRK1MAPTMAPK1 | |
| SCHEMBL17806419 | 0.79 | MAPT (0.48) | ALDH1A1OPRK1MAPTMAPK1POLB | |
| SCHEMBL17222837 | 0.78 | ALDH1A1 (0.44) | PKMALDH1A1LMNAMAPTHTT | |
| SCHEMBL221671 | 0.78 | ALDH1A1 (0.44) | PKMALDH1A1LMNAMAPTHTT | |
| SCHEMBL23714349 | 0.76 | MAPK1 (0.47) | PKMALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL4719832 | 0.76 | ALDH1A1 (0.46) | PKMALDH1A1LMNAMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9832999-B1 | Bicyclic compounds as pest control agents | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-12-05 | — | — | US | disclosed |
| US-20170325458-A1 | BICYCLIC COMPOUNDS AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170325458-A1 | BICYCLIC COMPOUNDS AS PEST CONTROL AGENTS | DDT, BCHE, BAK1 | PKM 1115/4885ALDH1A1 3812/4885LMNA 846/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.