SCHEMBL1960130

SCHEMBL1960130

CCCCc1nc2c(N)nc3ccccc3c2n1CCCOC(N)=O

nearest known ligand 0.70

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 20/20 0.70
TLR8 Q9NR97 4/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29034534 0.97 TLR7 (0.71) TLR7TLR8
SCHEMBL3673427 0.90 TLR7 (0.59) TLR7TLR8
SCHEMBL12003054 0.87 TLR8 (0.68) TLR7TLR8
SCHEMBL5616930 0.87 TLR7 (0.77) TLR7TLR8
SCHEMBL20623370 0.85 TLR7 (0.89) TLR7TLR8
SCHEMBL25950861 0.85 TLR7 (0.71) TLR7TLR8
SCHEMBL4143809 0.85 TLR7 (0.74) TLR7TLR8
SCHEMBL2897067 0.84 TLR7 (0.80) TLR7TLR8
SCHEMBL6135641 0.84 TLR7 (0.73) TLR7TLR8
SCHEMBL10147925 0.84 TLR7 (0.84) TLR7TLR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2507237-A1 IMIDAZOQUINOLINES WHICH ACT VIA TOLL - LIKE RECEPTORS (TLR) Dainippon Sumitomo Pharma Co., Ltd. (JP) 2012-10-10 EP disclosed
WO-2011068233-A1 IMIDAZOQUINOLINES WHICH ACT VIA TOLL - LIKE RECEPTORS (TLR) DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) 2011-06-09 WO disclosed