Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GGPS1 | O95749 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19450514 | 0.90 | KDM4E (0.41) | ABCB1KDM4EL3MBTL1GGPS1 | |
| SCHEMBL79622 | 0.84 | TSHR (0.37) | KDM4EL3MBTL1TSHR | |
| SCHEMBL10283826 | 0.83 | KCNA5 (0.38) | ABCB1KDM4EL3MBTL1GGPS1 | |
| SCHEMBL20356793 | 0.83 | CA12 (0.46) | KDM4EL3MBTL1 | |
| SCHEMBL17383350 | 0.83 | KDM4E (0.34) | KDM4EL3MBTL1 | |
| SCHEMBL7528385 | 0.83 | KDM4E (0.50) | KDM4EL3MBTL1 | |
| SCHEMBL7147102 | 0.81 | CA12 (0.50) | KDM4EL3MBTL1 | |
| SCHEMBL3930915 | 0.81 | CA12 (0.50) | KDM4EL3MBTL1 | |
| SCHEMBL3921745 | 0.81 | CA12 (0.50) | KDM4EL3MBTL1 | |
| SCHEMBL15836119 | 0.79 | PIK3CD (0.43) | ABCB1KDM4EL3MBTL1GGPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170326149-A1 | HYDROXYL PURINE COMPOUNDS AND APPLICATIONS THEREOF | GUANGDONG ZHONGSHENG PHARMACEUTICAL CO., LTD (CN) | 2017-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170326149-A1 | HYDROXYL PURINE COMPOUNDS AND APPLICATIONS THEREOF | PNP, PDE2A, PDE7A | ABCB1 379/4885KDM4E 4302/4885L3MBTL1 4846/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.