SCHEMBL1960367

SCHEMBL1960367

CCCCCCCCCNC(=O)CC#N

nearest known ligand 0.71

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 2/20 0.71
CASP2 P42575 1/20 0.60
NAAA Q02083 1/20 0.56
EPHX1 P07099 7/20 0.55
FAAH O00519 2/20 0.51
ZDHHC20 Q5W0Z9 2/20 0.49
ZDHHC2 Q9UIJ5 2/20 0.49
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
EPHX2 P34913 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1960248 1.00 MCL1 (0.71) MCL1CASP2NAAAEPHX1FAAH
SCHEMBL1962966 1.00 MCL1 (0.71) MCL1CASP2NAAAEPHX1FAAH
SCHEMBL1958608 1.00 MCL1 (0.71) MCL1CASP2NAAAEPHX1FAAH
SCHEMBL6320829 1.00 MCL1 (0.71) MCL1CASP2NAAAEPHX1FAAH
SCHEMBL1962363 1.00 MCL1 (0.71) MCL1CASP2NAAAEPHX1FAAH
SCHEMBL1961150 1.00 MCL1 (0.71) MCL1CASP2NAAAEPHX1FAAH
SCHEMBL3394896 1.00 MCL1 (0.71) MCL1CASP2NAAAEPHX1FAAH
SCHEMBL1961539 1.00 MCL1 (0.71) MCL1CASP2NAAAEPHX1FAAH
SCHEMBL1962964 1.00 MCL1 (0.71) MCL1CASP2NAAAEPHX1FAAH
SCHEMBL1958356 1.00 MCL1 (0.71) MCL1CASP2NAAAEPHX1FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9976103-B2 Lubricating composition containing an antiwear agent THE LUBRIZOL CORPORATION (US) 2018-05-22 US disclosed
EP-2513269-B1 LUBRICATING COMPOSITION CONTAINING AN ANTIWEAR AGENT LUBRIZOL CORP (US) 2017-10-25 EP disclosed
US-9708563-B2 Lubricating composition containing an antiwear agent THE LUBRIZOL CORPORATION (US) 2017-07-18 US disclosed
US-20150267140-A1 LUBRICATING COMPOSITION CONTAINING AN ANTIWEAR AGENT LUBRIZOL CORP (US) 2015-09-24 US disclosed
US-20130172221-A1 Lubricating Composition Containing an Antiwear Agent THE LUBRIZOL CORPORATION (US) 2013-07-04 US disclosed
US-20120309657-A1 Lubricating Composition Containing an Antiwear Agent THE LUBRIZOL CORPORATION (US) 2012-12-06 US disclosed
EP-2513272-A1 LUBRICATING COMPOSITION CONTAINING AN ANTIWEAR AGENT The Lubrizol Corporation (US) 2012-10-24 EP disclosed
EP-2513269-A1 LUBRICATING COMPOSITION CONTAINING AN ANTIWEAR AGENT The Lubrizol Corporation (US) 2012-10-24 EP disclosed
WO-2011081835-A1 LUBRICATING COMPOSITION CONTAINING AN ANTIWEAR AGENT THE LUBRIZOL CORPORATION (US) 2011-07-07 WO disclosed
WO-2011075403-A1 LUBRICATING COMPOSITION CONTAINING AN ANTIWEAR AGENT THE LUBRIZOL CORPORATION (US) 2011-06-23 WO disclosed
US-20040254241-A1 Enzyme inhibitor; cognition activators KYOWA HAKKO KOGYO CO., LTD. (JP) 2004-12-16 US disclosed
EP-1431280-A1 ARYL SULFAMATE DERIVATIVES Kyowa Hakko Kogyo Co., Ltd (JP) 2004-06-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040254241-A1 Enzyme inhibitor; cognition activators SULT1A1, STS, CYP26A1 MCL1 4226/4885CASP2 2385/4885NAAA 148/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.