SCHEMBL196046

SCHEMBL196046

CCOC(=O)c1c(F)c(F)c(F)c(F)c1F

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.53
SMN1; SMN2 Q16637 4/20 0.53
RAB9A P51151 3/20 0.53
NPSR1 Q6W5P4 3/20 0.53
TP53 P04637 2/20 0.53
NPC1 O15118 2/20 0.53
HSD17B10 Q99714 2/20 0.53
MITF O75030 1/20 0.53
RECQL P46063 1/20 0.53
ALDH1A1 P00352 5/20 0.52
HPGD P15428 4/20 0.52
GAA P10253 3/20 0.52
MAPT P10636 3/20 0.52
CA12 O43570 1/20 0.52
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
CA7 P43166 1/20 0.52
CA9 Q16790 1/20 0.52
CA14 Q9ULX7 1/20 0.52
TDP1 Q9NUW8 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL522219 0.98 ESR1 (0.52) ESR1SMN1; SMN2RAB9ANPSR1TP53
SCHEMBL522227 0.98 ESR1 (0.55) ESR1SMN1; SMN2RAB9ANPSR1TP53
Alcohol SCHEMBL28160506 0.96 SMN1; SMN2 (0.50) ESR1SMN1; SMN2RAB9ANPSR1TP53
SCHEMBL6578769 0.95 SMN1; SMN2 (0.53) ESR1SMN1; SMN2RAB9ANPSR1TP53
SCHEMBL522265 0.89 ALDH1A1 (0.49) ESR1SMN1; SMN2RAB9ANPSR1TP53
SCHEMBL2458847 0.89 ESR1 (0.49) ESR1SMN1; SMN2RAB9ANPSR1TP53
SCHEMBL2454093 0.89 ESR1 (0.68) ESR1SMN1; SMN2RAB9ANPSR1TP53
SCHEMBL2451516 0.88 SMN1; SMN2 (0.45) ESR1SMN1; SMN2RAB9ANPSR1TP53
SCHEMBL7155146 0.87 ALDH1A1 (0.55) ESR1SMN1; SMN2RAB9ANPSR1TP53
SCHEMBL9785436 0.87 ESR1 (0.47) ESR1SMN1; SMN2RAB9ANPSR1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 209 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117946303-A Catalyst, preparation method thereof, method for regulating and controlling ethylene polymerization kinetics behavior and application 中国石油化工股份有限公司 2024-04-30 CN claimed
CN-105925246-A Electricity generated acid produced by blending substances with changeable oxidation state and electrolyte and applications thereof 吉林大学 2016-09-07 CN claimed
US-8952083-B2 Fluorocopolymer composition and its production process ASAHI GLASS COMPANY, LIMITED (JP) 2015-02-10 US claimed
EP-2838129-B1 COMPOSITION FOR ORGANIC ELECTROLUMINESCENT ELEMENTS MITSUBISHI CHEM CORP (JP) 2026-03-18 EP disclosed
CN-118993958-A Method for synthesizing polyfluoroaryl sulfide 三峡大学 2024-11-22 CN disclosed
CN-118955560-A Light-induced polyfluoroaromatic hydrocarbon phosphonation process 南京师范大学 2024-11-15 CN disclosed
CN-116496493-B Polymer, composition for organic EL element, and method for producing same 三菱化学株式会社 2024-09-06 CN disclosed
CN-114729121-B Polymer, composition for organic electroluminescent element, composition for forming hole transport layer or hole injection layer, organic electroluminescent element, organic EL display device, and organic EL illumination 三菱化学株式会社 2024-08-02 CN disclosed
CN-117946304-A Spherical catalyst component containing fluoroester electron donor, preparation method, catalyst and application thereof in ethylene polymerization 中国石油化工股份有限公司 2024-04-30 CN disclosed
CN-117946303-A Catalyst, preparation method thereof, method for regulating and controlling ethylene polymerization kinetics behavior and application 中国石油化工股份有限公司 2024-04-30 CN disclosed
CN-113454141-B Polymer, organic electroluminescent element, organic EL display device, and organic EL illumination 三菱化学株式会社 2024-03-26 CN disclosed
US-20010033989-A1 Novel polymers, resist compositions and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2001-10-25 US disclosed
US-20010018162-A1 Novel polymers, chemical amplification resist compositions and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2001-08-30 US disclosed
EP-1126322-A2 Fluorine-containing polymers, resist compositions and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2001-08-22 EP disclosed
EP-0266947-B1 HALOGENATED ESTERS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-12-04 EP disclosed
US-4853414-A 1-/2-ALKOXY-3,5-DIFLUOROBENZYL ESTERS OF 2,2-DIMETHYL-3-ALKYLCYCLOPROPIONIC ACID; INSECTICIDES; PESTICIDES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1989-08-01 US disclosed
EP-0266947-A2 Halogenated esters IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1988-05-11 EP disclosed
US-4333940-A Ring-fluorinated 4-(monosubstituted-amino) phenyl compounds in inhibiting atherosclerotic lesion development AMERICAN CYANAMID COMPANY (US) 1982-06-08 US disclosed
US-4243609-A ANTILIPEMIC AGENTS, ANTIATHEROSCLEROTIC AGENTS AMERICAN CYANAMID COMPANY (US) 1981-01-06 US disclosed
EP-0003663-A2 Amino-substituted phenyl and heteroaryl compounds, process for their preparation and pharmaceutical compositions containing them AMERICAN CYANAMID COMPANY (US) 1979-08-22 EP disclosed