Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP2 | P42575 | 1/20 | 0.61 |
| ▸ | NAAA | Q02083 | 1/20 | 0.57 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | FAAH | O00519 | 2/20 | 0.52 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22340820 | 0.98 | CASP2 (0.64) | CASP2NAAAEPHX1MEN1KMT2A | |
| SCHEMBL25950981 | 0.98 | CASP2 (0.64) | CASP2NAAAEPHX1MEN1KMT2A | |
| SCHEMBL21613628 | 0.98 | CASP2 (0.64) | CASP2NAAAEPHX1MEN1KMT2A | |
| SCHEMBL11014644 | 0.98 | CASP2 (0.64) | CASP2NAAAEPHX1MEN1KMT2A | |
| SCHEMBL8209484 | 0.93 | CASP2 (0.52) | CASP2NAAAEPHX1MEN1KMT2A | |
| SCHEMBL25449079 | 0.89 | EPHX2 (0.65) | LPAR1EPHX2 | |
| SCHEMBL11832089 | 0.89 | EPHX2 (0.65) | LPAR1EPHX2 | |
| SCHEMBL25091844 | 0.88 | CASP2 (0.68) | CASP2NAAAMEN1KMT2AFAAH | |
| SCHEMBL25477974 | 0.87 | S1PR2 (0.53) | CASP2NAAAEPHX1FAAH | |
| SCHEMBL25140466 | 0.86 | MEN1 (0.52) | CASP2NAAAEPHX1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4227315-A1 | COMPOUND TARGETING PROSTATE SPECIFIC MEMBRANE ANTIGEN, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Yantai Lannacheng Biotechnology Co., Ltd. (CN) | 2023-08-16 | — | — | EP | disclosed |
| US-20230146870-A1 | METHOD TO QUANTIFY AFFINITY AND SELECTIVITY OF SMALL MOLECULES FOR PROTEINS IN LIVING CELLS | OHIO STATE INNOVATION FOUNDATION | 2023-05-11 | — | — | US | disclosed |
| WO-2017197051-A1 | AMINE-LINKED C3-GLUTARIMIDE DEGRONIMERS FOR TARGET PROTEIN DEGRADATION | C4 THERAPEUTICS, INC. (US) | 2017-11-16 | — | — | WO | disclosed |