Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 18/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2506487 | 0.82 | BCL2 (0.42) | BCL2 | |
| SCHEMBL1956186 | 0.81 | BCL2 (0.49) | BCL2BCL2L1 | |
| SCHEMBL1954915 | 0.81 | BCL2 (0.43) | BCL2BCL2L1 | |
| SCHEMBL1960826 | 0.80 | BCL2 (0.55) | BCL2BCL2L1 | |
| SCHEMBL17419440 | 0.80 | BCL2 (0.45) | BCL2BCL2L1 | |
| SCHEMBL2480519 | 0.74 | MAPT (0.39) | BCL2BCL2L1MAPTMAPK1 | |
| SCHEMBL1955330 | 0.74 | BCL2 (0.61) | BCL2BCL2L1 | |
| SCHEMBL30112869 | 0.71 | BCL2L1 (0.58) | BCL2BCL2L1MAPTMAPK1 | |
| SCHEMBL1957676 | 0.70 | BCL2 (0.47) | BCL2MAPT | |
| SCHEMBL1958955 | 0.69 | BCL2 (0.48) | BCL2BCL2L1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2507211-A1 | APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES | Abbott Laboratories (US) | 2012-10-10 | — | — | EP | claimed |
| WO-2011068560-A1 | APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES | ABBOTT LABORATORIES (US) | 2011-06-09 | — | — | WO | claimed |