Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 17/20 | 0.42 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1960829 | 0.82 | BCL2 (0.41) | BCL2 | |
| SCHEMBL2506488 | 0.80 | BCL2 (0.57) | BCL2 | |
| SCHEMBL3419072 | 0.80 | BCL2 (0.42) | BCL2 | |
| SCHEMBL2480796 | 0.76 | BCL2 (0.45) | BCL2 | |
| SCHEMBL2507853 | 0.75 | ALDH3A1 (0.42) | — | |
| SCHEMBL1956186 | 0.75 | BCL2 (0.49) | BCL2 | |
| SCHEMBL1954915 | 0.74 | BCL2 (0.43) | BCL2 | |
| SCHEMBL2503120 | 0.74 | BCL2 (0.63) | BCL2 | |
| SCHEMBL1958128 | 0.73 | BCL2 (0.38) | BCL2HCAR3 | |
| SCHEMBL3398580 | 0.69 | ALDH3A1 (0.39) | BCL2HCAR3MEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2376197-A2 | APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES | Abbott Laboratories (US) | 2011-10-19 | — | — | EP | claimed |
| WO-2010065824-A2 | APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES | ABBOTT LABORATORIES (US) | 2010-06-10 | — | — | WO | claimed |