SCHEMBL19608971

SCHEMBL19608971

Cc1ccccc1-c1c2ccccc2c(C=O)c2ccccc12

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PADI4 Q9UM07 1/20 0.42
ALDH1A1 P00352 4/20 0.42
TSHR P16473 1/20 0.42
BRD4 O60885 1/20 0.40
TRIM24 O15164 1/20 0.40
TRIM33 Q9UPN9 1/20 0.40
KDM4E B2RXH2 1/20 0.38
TP53 P04637 1/20 0.38
GAA P10253 1/20 0.38
HPGD P15428 1/20 0.38
HSD17B10 Q99714 1/20 0.38
ERN1 O75460 2/20 0.38
MAPK14 Q16539 1/20 0.37
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA9 Q16790 1/20 0.37
TACR1 P25103 1/20 0.35
CYP1A2 P05177 2/20 0.34
CYP2A6 P11509 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7123301 0.83 CYP1A2 (0.48) ALDH1A1TSHRBRD4KDM4ETP53
SCHEMBL19608999 0.82 PADI4 (0.44) PADI4ALDH1A1TSHRTRIM24TRIM33
SCHEMBL19609000 0.77 ERN1 (0.47) PADI4KDM4EGAAERN1CA12
SCHEMBL30032733 0.77 ERN1 (0.47) PADI4KDM4EGAAERN1CA12
SCHEMBL29588097 0.76 PADI4 (0.64) PADI4ALDH1A1KDM4EERN1CYP1A2
SCHEMBL986883 0.76 PADI4 (0.64) PADI4ALDH1A1KDM4EERN1CYP1A2
SCHEMBL11302952 0.75 PADI4 (0.48) PADI4ALDH1A1TSHRKDM4EERN1
SCHEMBL4164444 0.74 PADI4 (0.52) PADI4ALDH1A1TSHRKDM4EHPGD
SCHEMBL29802335 0.74 PADI4 (0.52) PADI4ALDH1A1TSHRKDM4EHPGD
SCHEMBL3722165 0.74 CYP1A2 (0.43) ALDH1A1TSHRBRD4KDM4ETP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017193288-A1 SYNTHESIS OF PHOSPHINE LIGANDS BEARING TUNABLE LINKAGE: METHODS OF THEIR USE IN CATALYSIS THE HONG KONG POLYTECHNIC UNIVERSITY SHENZHEN RESEARCH INSTITUTE (CN) 2017-11-16 WO disclosed