SCHEMBL7123301

SCHEMBL7123301

Cc1ccccc1-c1c2ccccc2c(-c2ccccc2C)c2ccccc12

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 4/20 0.48
CYP2A6 P11509 2/20 0.48
TSHR P16473 2/20 0.47
ACHE P22303 1/20 0.47
ALDH1A1 P00352 2/20 0.46
BRD4 O60885 1/20 0.45
NPC1 O15118 1/20 0.44
CASP3 P42574 1/20 0.44
RAB9A P51151 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
SENP8 Q96LD8 1/20 0.44
SENP7 Q9BQF6 1/20 0.44
SENP6 Q9GZR1 1/20 0.44
ADORA2A P29274 1/20 0.42
KIF11 P52732 1/20 0.41
MAPK14 Q16539 1/20 0.41
CYP2D6 P10635 2/20 0.40
CYP2C19 P33261 2/20 0.40
CLK4 Q9HAZ1 2/20 0.40
HSD17B10 Q99714 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3722165 0.90 CYP1A2 (0.43) CYP1A2CYP2A6TSHRACHEALDH1A1
SCHEMBL21224352 0.89 ACHE (0.45) CYP1A2CYP2A6TSHRACHEALDH1A1
SCHEMBL18568466 0.89 BRD4 (0.39) CYP1A2CYP2A6TSHRACHEALDH1A1
SCHEMBL8865515 0.84 CYP1A2 (0.52) CYP1A2CYP2A6TSHRALDH1A1BRD4
SCHEMBL19608971 0.83 PADI4 (0.42) CYP1A2CYP2A6TSHRALDH1A1BRD4
SCHEMBL29152146 0.83 LMNA (0.45) CYP1A2TSHRALDH1A1BRD4NPC1
SCHEMBL18627755 0.82 MAPK14 (0.45) CYP1A2CYP2A6TSHRACHEALDH1A1
SCHEMBL19608972 0.82 ADORA2A (0.56) CYP1A2TSHRACHEALDH1A1NPC1
SCHEMBL1102630 0.82 MAPK14 (0.46) CYP1A2TSHRACHEALDH1A1NPC1
SCHEMBL28957474 0.82 MAP2 (0.50) CYP1A2CYP2A6TSHRALDH1A1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003031937-A2 GENETIC HYPERMUTABILITY OF PLANTS FOR GENE DISCOVERY AND DIAGNOSIS MORPHOTEK, INC. (US) 2003-04-17 WO claimed
US-11723265-B2 Organic light emitting diode with high efficiency SFC CO., LTD. (KR) 2023-08-08 US disclosed
US-20200168803-A1 Organic light emitting diode with high efficiency SFC CO., LTD. (KR) 2020-05-28 US disclosed