Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 8/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | EZH2 | Q15910 | 2/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | TLR2 | O60603 | 1/20 | 0.36 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2549491 | 0.83 | KDM1A (0.53) | KDM1AEZH2MAOAMAOB | |
| SCHEMBL2755941 | 0.82 | KDM1A (0.46) | KDM1AHDAC8HDAC6EZH2RORC | |
| SCHEMBL237030 | 0.82 | KDM1A (0.46) | KDM1AHDAC8HDAC6EZH2RORC | |
| SCHEMBL237029 | 0.82 | KDM1A (0.46) | KDM1AHDAC8HDAC6EZH2RORC | |
| SCHEMBL19609202 | 0.80 | KDM1A (0.43) | KDM1AHDAC8HDAC6EZH2MAOA | |
| SCHEMBL18845248 | 0.80 | KDM1A (0.43) | KDM1AHDAC8HDAC6EZH2MAOA | |
| SCHEMBL19585902 | 0.79 | KDM1A (0.48) | KDM1AHDAC8HDAC6MAOAMAOB | |
| SCHEMBL19609354 | 0.79 | KDM1A (0.46) | KDM1AHDAC8HDAC6MAOAMAOB | |
| SCHEMBL12242253 | 0.79 | MAOA (0.44) | KDM1AHDAC8HDAC6RORCHSD11B1 | |
| SCHEMBL2339013 | 0.78 | KDM1A (0.58) | KDM1AMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017195216-A1 | CYCLOPROPYL-AMIDE COMPOUNDS AS DUAL LSD1/HDAC INHIBITORS | JUBILANT BIOSYS LIMITED (IN) | 2017-11-16 | — | — | WO | disclosed |