Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 18/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19610436 | 0.89 | PTGER1 (0.43) | PTGER1CYP1A2PTGDR2 | |
| SCHEMBL15051955 | 0.87 | PTGER1 (0.43) | PTGER1CYP1A2TP53MAPT | |
| SCHEMBL15052004 | 0.83 | ALDH1A1 (0.53) | PTGER1CYP1A2TP53MAPT | |
| SCHEMBL15052055 | 0.80 | PTGER1 (0.46) | PTGER1CYP1A2 | |
| SCHEMBL15052180 | 0.79 | PTGER1 (0.52) | PTGER1CYP1A2 | |
| SCHEMBL15052433 | 0.79 | PTGER1 (0.43) | PTGER1CYP1A2PTGDR2 | |
| SCHEMBL19610402 | 0.79 | PTGER1 (0.44) | PTGER1CYP1A2 | |
| SCHEMBL19610400 | 0.77 | PTGER1 (0.47) | PTGER1 | |
| SCHEMBL19610429 | 0.77 | PTGER1 (0.48) | PTGER1CYP1A2PTGDR2 | |
| SCHEMBL15076280 | 0.77 | PTGER1 (0.41) | PTGER1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2797893-B1 | COMPOUNDS ACTING AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE | ALLERGAN INC (US) | 2017-11-22 | — | — | EP | claimed |