Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 1/20 | 0.72 |
| ▸ | FABP4 | P15090 | 1/20 | 0.72 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | LDHA | P00338 | 2/20 | 0.40 |
| ▸ | LDHB | P07195 | 2/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
| ▸ | ALB | P02768 | 3/20 | 0.37 |
| ▸ | EIF4A3 | P38919 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | RXRG | P48443 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17935194 | 0.92 | CA1 (0.68) | FABP3FABP4CA1CA2LDHA | |
| SCHEMBL28708940 | 0.90 | FABP3 (0.78) | FABP3FABP4CA1CA2LDHA | |
| SCHEMBL810177 | 0.84 | FABP3 (1.00) | FABP3FABP4LDHALDHBACE2 | |
| SCHEMBL14273020 | 0.84 | FABP3 (0.69) | FABP3FABP4CA1CA2LDHA | |
| SCHEMBL17323547 | 0.84 | FABP3 (0.69) | FABP3FABP4LDHALDHBACE2 | |
| SCHEMBL17311830 | 0.82 | FABP3 (0.96) | FABP3FABP4LDHALDHBACE2 | |
| SCHEMBL10360591 | 0.80 | FABP3 (0.64) | FABP3FABP4LDHALDHBACE2 | |
| SCHEMBL9857114 | 0.80 | FABP3 (0.49) | FABP3FABP4CA1CA2GABRA1 | |
| SCHEMBL19164751 | 0.79 | FABP3 (0.63) | FABP3FABP4CA1CA2LDHA | |
| SCHEMBL6637397 | 0.76 | FABP3 (0.59) | FABP3FABP4CA1CA2GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10329243-B2 | Biphenyl derivative and uses thereof | XI'AN LIBANG PHARMACEUTICAL CO., LTD (CN) | 2019-06-25 | — | — | US | disclosed |
| US-20180141895-A1 | DIPHENYL DERIVATIVE AND USES THEREOF | XI'AN LIBANG PHARMACEUTICAL CO., LTD (CN) | 2018-05-24 | — | — | US | disclosed |
| EP-3246304-A2 | DIPHENYL DERIVATIVE AND USES THEREOF | Xi'an Libang Pharmaceutical Co., Ltd (CN) | 2017-11-22 | — | — | EP | disclosed |
| CN-104557532-B | Bigeminy benzene derivative and its application | 西安力邦制药有限公司 | 2017-03-01 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10329243-B2 | Biphenyl derivative and uses thereof | PPARD, PCSK9, UGT2B7 | FABP3 15/4885FABP4 258/4885CA1 2711/4885 |
| US-20180141895-A1 | DIPHENYL DERIVATIVE AND USES THEREOF | PPARD, DPP3, DPP7 | FABP3 46/4885FABP4 629/4885CA1 2497/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.