Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 20/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19611089 | 0.88 | ADORA2B (0.62) | ADORA2B | |
| SCHEMBL16643994 | 0.88 | ADORA2B (1.00) | ADORA2B | |
| SCHEMBL19611062 | 0.86 | ADORA2B (0.64) | ADORA2B | |
| SCHEMBL18096973 | 0.86 | ADORA2B (0.85) | ADORA2B | |
| SCHEMBL18097008 | 0.85 | ADORA2B (1.00) | ADORA2B | |
| SCHEMBL18135151 | 0.85 | ADORA2B (0.83) | ADORA2B | |
| SCHEMBL16637752 | 0.85 | ADORA2B (0.62) | ADORA2B | |
| SCHEMBL16637918 | 0.84 | ADORA2B (0.56) | ADORA2B | |
| SCHEMBL14936059 | 0.84 | ADORA2B (1.00) | ADORA2B | |
| SCHEMBL19923959 | 0.84 | ADORA2B (0.89) | ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3274352-B1 | HETEROCYCLYLMETHYL-THIENOURACILE AS ANTAGONISTS OF THE ADENOSINE-A2B-RECEPTOR | Bayer Pharma AG (DE) | 2019-01-02 | — | — | EP | disclosed |
| EP-3055313-B1 | CYCLIC THIENOURACIL CARBOXAMIDE AND ITS USE | Bayer Pharma AG (DE) | 2017-11-22 | — | — | EP | disclosed |