Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.31 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7155525 | 0.79 | TSHR (0.36) | ALDH1A1AKT1TSHR | |
| SCHEMBL7945317 | 0.78 | — | — | |
| SCHEMBL22607712 | 0.77 | EGLN1 (0.34) | EGLN1ALDH1A1AKT1TGFBR1TET2 | |
| SCHEMBL27568373 | 0.74 | GRIK1 (0.36) | EGLN1ALDH1A1TGFBR1TET2TSHR | |
| SCHEMBL27582592 | 0.73 | GRIK1 (0.39) | EGLN1ALDH1A1TGFBR1TET2 | |
| SCHEMBL27568066 | 0.71 | EP300 (0.44) | TSHR | |
| SCHEMBL3041579 | 0.71 | — | — | |
| SCHEMBL3041576 | 0.71 | — | — | |
| SCHEMBL11409721 | 0.70 | ALDH1A1 (0.38) | ALDH1A1AKT1HCAR2KEAP1NFE2L2 | |
| SCHEMBL11409718 | 0.70 | ALDH1A1 (0.38) | ALDH1A1AKT1HCAR2KEAP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3461806-B1 | PROCESS FOR PREPARING ALFA-HYDROXY METHIONINE ANALOGUES FROM SUGARS | HALDOR TOPSOE AS (DK) | 2020-08-05 | — | — | EP | disclosed |
| EP-3224234-B1 | PROCESS FOR PREPARING ESTERS OF LACTIC ACID AND 2-HYDROXY-3-BUTENOIC ACID FROM SUGARS | HALDOR TOPSOE AS (DK) | 2019-08-14 | — | — | EP | disclosed |
| US-10343986-B2 | Process for preparing esters of lactic acid, and 2-hydroxy-3-butenoic acid from sugars | HALDOR TOPSOE A/S (DK) | 2019-07-09 | — | — | US | disclosed |
| US-10280136-B2 | Process for preparing esters of α-hydroxy methionine from sugars | HALDOR TOPSOE A/S (DK) | 2019-05-07 | — | — | US | disclosed |
| EP-3461806-A1 | PROCESS FOR PREPARING ESTERS OF LACTIC ACID, AND 2-HYDROXY-3-BUTENOIC ACID OR ALFA-HYDROXY METHIONINE ANALOGUES FROM SUGARS | Haldor Topsøe A/S (DK) | 2019-04-03 | — | — | EP | disclosed |
| US-20190016674-A1 | PROCESS FOR PREPARING ESTERS OF LACTIC ACID, AND 2-HYDROXY-3-BUTENOIC ACID OR ALPHA-HYDROXY METHIONINE ANALOGUES FROM SUGARS | TOPSOE A/S (DK) | 2019-01-17 | — | — | US | disclosed |
| US-10100007-B2 | Process for preparing esters of lactic acid, and 2-hydroxy-3-butenoic acid or α-hydroxy methionine analogues from sugars | HALDOR TOPSOE A/S (DK) | 2018-10-16 | — | — | US | disclosed |
| US-20170334844-A1 | PROCESS FOR PREPARING ESTERS OF LACTIC ACID, AND 2-HYDROXY-3-BUTENOIC ACID OR ALPHA-HYDROXY METHIONINE ANALOGUES FROM SUGARS | HALDOR TOPSØE A/S (DK) | 2017-11-23 | — | — | US | disclosed |