SCHEMBL19612295

SCHEMBL19612295

Oc1cccc2c(O)c(Cl)ccc12

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.46
CYP1A2 P05177 4/20 0.44
HPGD P15428 3/20 0.44
HSD17B10 Q99714 3/20 0.44
TSHR P16473 2/20 0.44
ALOX15 P16050 2/20 0.44
RECQL P46063 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
MAPT P10636 2/20 0.44
APP P05067 1/20 0.44
THRB P10828 1/20 0.44
CASP1 P29466 1/20 0.44
SNCA P37840 1/20 0.44
AR P10275 1/20 0.44
HSD17B1 P14061 1/20 0.43
HSD17B2 P37059 1/20 0.43
ALDH1A1 P00352 3/20 0.42
LMNA P02545 4/20 0.42
CDK2 P24941 2/20 0.42
ADAMTS4 O75173 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2477256 0.83 DPP4 (0.46) CYP1A2HPGDHSD17B10TSHRALOX15
SCHEMBL5356189 0.82 TSHR (0.56) IDO1CYP1A2HPGDHSD17B10TSHR
SCHEMBL31434175 0.82 TSHR (0.56) IDO1CYP1A2HPGDHSD17B10TSHR
SCHEMBL5346560 0.78 NR4A2 (0.59) IDO1CYP1A2HPGDHSD17B10TSHR
SCHEMBL4960152 0.78 CYP1A2 (0.68) IDO1CYP1A2HPGDHSD17B10TSHR
SCHEMBL31037123 0.78 IDO1 (0.60) IDO1CYP1A2HPGDHSD17B10TSHR
SCHEMBL2994806 0.78 IDO1 (0.60) IDO1CYP1A2HPGDHSD17B10TSHR
SCHEMBL16107538 0.77 IDO1 (0.65) IDO1CYP1A2HPGDHSD17B10TSHR
SCHEMBL29351230 0.77 IDO1 (0.73) IDO1CYP1A2HPGDHSD17B10TSHR
SCHEMBL4869305 0.77 IDO1 (0.73) IDO1CYP1A2HPGDHSD17B10TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170336728-A1 ULTRAVIOLET CURABLE LIQUID COMPOSITION, ULTRAVIOLET CURING INKJET INK, ULTRAVIOLET CURING WET ELECTROPHOTOGRAPHIC LIQUID DEVELOPER, ULTRAVIOLET CURING ELECTROSTATIC INKJET INK, AND IMAGE FORMING METHOD USING THEREOF CANON KABUSHIKI KAISHA (JP) 2017-11-23 US disclosed