SCHEMBL19612485

SCHEMBL19612485

COc1cc2ccc(OCc3ccccc3)cc2cc1OCc1ccccc1

nearest known ligand 0.65

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.65
PDGFRB P09619 1/20 0.63
PDGFRA P16234 1/20 0.63
MAOB P27338 1/20 0.57
SRD5A1 P18405 2/20 0.53
SRD5A2 P31213 2/20 0.53
MEN1 O00255 1/20 0.50
NPC1 O15118 1/20 0.50
RAB9A P51151 1/20 0.50
KMT2A Q03164 1/20 0.50
CYP3A4 P08684 1/20 0.50
ALDH1A1 P00352 1/20 0.50
LMNA P02545 1/20 0.50
MAPT P10636 1/20 0.50
ALOX12 P18054 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
CHRNA7 P36544 2/20 0.49
FLT3 P36888 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19612478 1.00 ALOX5 (0.65) ALOX5PDGFRBPDGFRAMAOBSRD5A1
SCHEMBL7827220 0.94 PDGFRB (0.59) ALOX5PDGFRBPDGFRAMAOBSRD5A1
SCHEMBL18623122 0.85 MAOB (0.62) ALOX5PDGFRBPDGFRAMAOBMEN1
SCHEMBL2090976 0.85 MAOB (0.62) ALOX5PDGFRBPDGFRAMAOBKMT2A
SCHEMBL28103389 0.85 PDGFRB (0.57) ALOX5PDGFRBPDGFRAMAOBMEN1
SCHEMBL17912806 0.84 ALOX5 (0.65) ALOX5PDGFRBPDGFRAMAOBMEN1
SCHEMBL17912842 0.84 ALOX5 (0.65) ALOX5PDGFRBPDGFRAMAOBMEN1
SCHEMBL17912803 0.84 ALOX5 (0.65) ALOX5PDGFRBPDGFRAMAOBMEN1
SCHEMBL19612216 0.84 ALOX5 (0.65) ALOX5PDGFRBPDGFRAMAOBMEN1
SCHEMBL5753220 0.84 SRD5A1 (0.53) PDGFRBPDGFRASRD5A1SRD5A2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170336728-A1 ULTRAVIOLET CURABLE LIQUID COMPOSITION, ULTRAVIOLET CURING INKJET INK, ULTRAVIOLET CURING WET ELECTROPHOTOGRAPHIC LIQUID DEVELOPER, ULTRAVIOLET CURING ELECTROSTATIC INKJET INK, AND IMAGE FORMING METHOD USING THEREOF CANON KABUSHIKI KAISHA (JP) 2017-11-23 US disclosed