SCHEMBL196132

SCHEMBL196132

CC(NC(=O)c1cc(Cl)cc(Cl)c1NC(=O)c1cc(Br)nn1-c1ncccc1Cl)C1CC1

nearest known ligand 0.64

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 3/20 0.38
DHODH Q02127 3/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
NAMPT P43490 2/20 0.37
MALT1 Q9UDY8 6/20 0.35
RIPK1 Q13546 1/20 0.35
CNR1 P21554 2/20 0.34
CNR2 P34972 2/20 0.34
DRD4 P21917 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29416624 1.00 IDO1 (0.38) IDO1DHODHNPC1RAB9ANAMPT
SCHEMBL230723 0.94 IDO1 (0.38) IDO1DHODHNPC1RAB9ANAMPT
SCHEMBL29355401 0.94 IDO1 (0.38) IDO1DHODHNPC1RAB9ANAMPT
SCHEMBL27174182 0.94 IDO1 (0.38) IDO1DHODHNPC1RAB9ANAMPT
SCHEMBL29416636 0.94 IDO1 (0.38) IDO1DHODHNPC1RAB9ANAMPT
SCHEMBL195314 0.94 DHODH (0.40) IDO1DHODHNPC1RAB9ANAMPT
SCHEMBL29416550 0.94 DHODH (0.40) IDO1DHODHNPC1RAB9ANAMPT
SCHEMBL27921983 0.91 IDO1 (0.36) IDO1DHODHNPC1RAB9ANAMPT
SCHEMBL29416604 0.91 IDO1 (0.36) IDO1DHODHNAMPTRIPK1CNR1
SCHEMBL195661 0.91 IDO1 (0.36) IDO1DHODHNAMPTRIPK1CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011147952-A1 PESTICIDAL MIXTURES BASF SE (DE) 2011-12-01 WO claimed
JP-2011527307-A 2011-10-27 JP claimed
US-20110224075-A1 Pesticidal Active Mixtures Comprising Aminothiazoline Compounds BASF SE (DE) 2011-09-15 US claimed
US-20110118212-A1 Pestcidal active mixtures comprising isoxazoline compounds I BASF SE (DE) 2011-05-19 US claimed
EP-2306837-A1 PESTCIDAL ACTIVE MIXTURES COMPRISING ISOXAZOLINE COMPOUNDS I BASF SE (DE) 2011-04-13 EP claimed
EP-2273883-A2 PESTICIDAL ACTIVE MIXTURES COMPRISING AMINOTHIAZOLINE COMPOUNDS BASF SE (DE) 2011-01-19 EP claimed
US-10231455-B2 Pesticidal active mixtures comprising isoxazoline compounds I BASF SE (DE) 2019-03-19 US disclosed
US-20180007904-A1 Pesticidal Active Mixtures Comprising Isoxazoline Compounds I BASF SE (DE) 2018-01-11 US disclosed
US-8716182-B2 Liquid aqueous crop protection formulations BASF SE (DE) 2014-05-06 US disclosed
US-8563474-B2 Pestcidal active mixtures comprising isoxazoline compounds I BASF SE (DE) 2013-10-22 US disclosed
US-20130203821-A1 Pyridine Compounds for Controlling Invertebrate Pests II BASF SE (DE) 2013-08-08 US disclosed
US-8221775-B2 Pyrrolin-2-ylamino compounds for combating animal pests BASF SE (DE) 2012-07-17 US disclosed
US-20120053052-A1 3-Arylquinazolin-4-one compounds for combating invertebrate pests BASF SE (DE) 2012-03-01 US disclosed
EP-2313381-A1 AZOLIN-2-YLAMINO COMPOUNDS FOR COMBATING ANIMAL PESTS BASF SE (DE) 2011-04-27 EP disclosed
EP-2306837-A1 PESTCIDAL ACTIVE MIXTURES COMPRISING ISOXAZOLINE COMPOUNDS I BASF SE (DE) 2011-04-13 EP disclosed
EP-2303874-A2 SULFONAMIDE COMPOUNDS BASF SE (DE) 2011-04-06 EP disclosed
WO-2011036074-A1 AMINOQUINAZOLINE COMPOUNDS FOR COMBATING INVERTEBRATE PESTS BASF SE (DE) 2011-03-31 WO disclosed
WO-2011009804-A2 PYRIDINE DERIVATIVES COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS BASF SE (DE) 2011-01-27 WO disclosed
EP-2273883-A2 PESTICIDAL ACTIVE MIXTURES COMPRISING AMINOTHIAZOLINE COMPOUNDS BASF SE (DE) 2011-01-19 EP disclosed
WO-2011003796-A1 PYRIDAZINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS BASF SE (DE) 2011-01-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130203821-A1 Pyridine Compounds for Controlling Invertebrate Pests II GRIN2A, NR2C2, GRIA2 IDO1 1420/4885DHODH 2526/4885NPC1 3632/4885
US-20110224075-A1 Pesticidal Active Mixtures Comprising Aminothiazoline Compounds CBR3, AOC3, MT-CO3 IDO1 428/4885DHODH 2236/4885NPC1 2841/4885
US-20110118212-A1 Pestcidal active mixtures comprising isoxazoline compounds I CHRM3, CHRM5, CHRM1 IDO1 705/4885DHODH 4306/4885NPC1 1729/4885
US-20180007904-A1 Pesticidal Active Mixtures Comprising Isoxazoline Compounds I CHRM3, CHRM5, CACNA1C IDO1 585/4885DHODH 4267/4885NPC1 2060/4885
US-10231455-B2 Pesticidal active mixtures comprising isoxazoline compounds I CHRM3, CHRM5, CACNA1C IDO1 585/4885DHODH 4267/4885NPC1 2060/4885
US-20120053052-A1 3-Arylquinazolin-4-one compounds for combating invertebrate pests CBR3, CNPY3, RTN3 IDO1 990/4885DHODH 4667/4885NPC1 1409/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.