SCHEMBL230723

SCHEMBL230723

CC(NC(=O)c1cc(Cl)cc(Br)c1NC(=O)c1cc(Br)nn1-c1ncccc1Cl)C1CC1

nearest known ligand 0.63

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.38
DHODH Q02127 3/20 0.37
NAMPT P43490 2/20 0.37
MALT1 Q9UDY8 7/20 0.35
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
PSD A5PKW4 1/20 0.35
RIPK1 Q13546 1/20 0.34
CNR1 P21554 2/20 0.34
CNR2 P34972 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29355401 1.00 IDO1 (0.38) IDO1DHODHNAMPTMALT1NPC1
SCHEMBL27174182 1.00 IDO1 (0.38) IDO1DHODHNAMPTMALT1NPC1
SCHEMBL29416636 1.00 IDO1 (0.38) IDO1DHODHNAMPTMALT1NPC1
SCHEMBL196132 0.94 IDO1 (0.38) IDO1DHODHNAMPTMALT1NPC1
SCHEMBL29416624 0.94 IDO1 (0.38) IDO1DHODHNAMPTMALT1NPC1
SCHEMBL195314 0.93 DHODH (0.40) IDO1DHODHNAMPTMALT1NPC1
SCHEMBL29416550 0.93 DHODH (0.40) IDO1DHODHNAMPTMALT1NPC1
SCHEMBL15034732 0.93 IDO1 (0.36) IDO1DHODHNAMPTMALT1NPC1
SCHEMBL4553452 0.92 IDO1 (0.42) IDO1DHODHNAMPTMALT1RIPK1
SCHEMBL516589 0.91 IDO1 (0.36) IDO1DHODHNAMPTMALT1RIPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1295 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4640053-A2 MIXTURES COMPRISING INDAZOLE PESTICIDES FMC Corporation (US) 2025-10-29 EP claimed
CN-108658816-B N-aryl amidine substituted trifluoroethyl sulfide derivatives useful as acaricides and insecticides 拜尔农作物科学股份公司 2023-05-02 CN claimed
US-20230026036-A1 DIAMIDE SUSPENSION CONCENTRATE COMPOSITIONS FMC IP TECHNOLOGY GMBH (CH) 2023-01-26 US claimed
EP-3887354-B1 META-DIAMIDE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS FMC CORP (US) 2023-01-04 EP claimed
US-20220394974-A1 MIXTURES COMPRISING INDAZOLE PESTICIDES FMC CORPORATION 2022-12-15 US claimed
EP-4013223-A1 MATERIAL DELIVERY SYSTEMS AND METHODS FMC Corporation (US) 2022-06-22 EP claimed
EP-3996508-A1 MIXTURES COMPRISING INDAZOLE PESTICIDES FMC Corporation (US) 2022-05-18 EP claimed
CN-114222498-A Material delivery system and method FMC公司 2022-03-22 CN claimed
EP-3887354-A1 META-DIAMIDE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS FMC Corporation (US) 2021-10-06 EP claimed
US-11076600-B2 Mixtures of cis-jasmone and bacillus amyloliquefaciens BASF SE (DE) 2021-08-03 US claimed
JP-2011527307-A 2011-10-27 JP claimed
US-20110224075-A1 Pesticidal Active Mixtures Comprising Aminothiazoline Compounds BASF SE (DE) 2011-09-15 US claimed
US-20110130427-A1 PESTICIDAL COMPOSITION ISHIHARA SANGYO KAISHA, LTD. (JP) 2011-06-02 US claimed
US-20110118212-A1 Pestcidal active mixtures comprising isoxazoline compounds I BASF SE (DE) 2011-05-19 US claimed
EP-2306837-A1 PESTCIDAL ACTIVE MIXTURES COMPRISING ISOXAZOLINE COMPOUNDS I BASF SE (DE) 2011-04-13 EP claimed
US-20110015237-A1 SOLID COMPOSITION FOR PEST CONTROL ISHIHARA SANGYO KAISHA, LTD. (JP) 2011-01-20 US claimed
US-20100317700-A1 PESTICIDAL COMPOSITIONS ISHIHARA SANGYO KAISHA LTD. (JP) 2010-12-16 US claimed
EP-2255625-A1 SOLID COMPOSITION FOR PEST CONTROL ISHIHARA SANGYO KAISHA, LTD. (JP) 2010-12-01 EP claimed
EP-2094087-A1 PESTICIDAL COMPOSITIONS ISHIHARA SANGYO KAISHA, LTD. (JP) 2009-09-02 EP claimed
WO-2008072783-A1 PESTICIDAL COMPOSITIONS ISHIHARA SANGYO KAISHA, LTD. (JP) 2008-06-19 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11076600-B2 Mixtures of cis-jasmone and bacillus amyloliquefaciens BAX, FASN, BAK1 IDO1 2472/4885DHODH 2795/4885NAMPT 2911/4885
US-20110224075-A1 Pesticidal Active Mixtures Comprising Aminothiazoline Compounds CBR3, AOC3, MT-CO3 IDO1 428/4885DHODH 2236/4885NAMPT 4274/4885
US-20100317700-A1 PESTICIDAL COMPOSITIONS ACHE, AAAS, AADAC IDO1 207/4885DHODH 1328/4885NAMPT 814/4885
US-20110118212-A1 Pestcidal active mixtures comprising isoxazoline compounds I CHRM3, CHRM5, CHRM1 IDO1 705/4885DHODH 4306/4885NAMPT 2176/4885
US-20110130427-A1 PESTICIDAL COMPOSITION PHOSPHO1, NAAA, NAPEPLD IDO1 1847/4885DHODH 2539/4885NAMPT 1139/4885
US-20220394974-A1 MIXTURES COMPRISING INDAZOLE PESTICIDES ACHE, DDT, BCHE IDO1 9/4885DHODH 2338/4885NAMPT 2836/4885
US-20110015237-A1 SOLID COMPOSITION FOR PEST CONTROL ANTXR2, STOM, SARAF IDO1 2550/4885DHODH 4143/4885NAMPT 1677/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.