Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19635451 | 0.84 | HCAR2 (0.32) | HCAR2 | |
| SCHEMBL24378198 | 0.81 | — | — | |
| SCHEMBL24378068 | 0.78 | HCAR2 (0.33) | HCAR2 | |
| SCHEMBL19635091 | 0.72 | PTPN1 (0.31) | — | |
| SCHEMBL24378111 | 0.72 | HCAR2 (0.30) | HCAR2 | |
| SCHEMBL19634996 | 0.69 | — | — | |
| SCHEMBL19634954 | 0.67 | KDM4E (0.41) | — | |
| SCHEMBL11826731 | 0.67 | HCAR2 (0.43) | HCAR2 | |
| SCHEMBL22816836 | 0.66 | HCAR2 (0.39) | HCAR2 | |
| SCHEMBL16846497 | 0.66 | DYRK1A (0.39) | HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3458459-A1 | MACROCYCLIC INDOLE DERIVATIVES | Bayer Aktiengesellschaft (DE) | 2019-03-27 | — | — | EP | disclosed |
| WO-2017198341-A1 | MACROCYCLIC INDOLE DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2017-11-23 | — | — | WO | disclosed |