Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | DAO | P14920 | 3/20 | 0.42 |
| ▸ | TKT | P29401 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | PI4KA | P42356 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL934661 | 0.83 | TRPV4 (0.48) | TRPV4KDM1AMAOAMAOBDAO | |
| SCHEMBL15284787 | 0.81 | TRPV4 (0.47) | TRPV4KDM1AMAOAMAOBDAO | |
| Hydrochloric Acid SCHEMBL4727675 | 0.80 | TRPV4 (0.46) | TRPV4KDM1AMAOAMAOBDAO | |
| SCHEMBL456310 | 0.79 | TRPV4 (0.52) | TRPV4KDM1AMAOAMAOBDAO | |
| SCHEMBL317731 | 0.79 | TRPV4 (0.52) | TRPV4KDM1AMAOAMAOBDAO | |
| SCHEMBL345116 | 0.75 | TRPV4 (0.52) | TRPV4KDM1AMAOAMAOBDAO | |
| SCHEMBL456311 | 0.75 | TRPV4 (0.57) | TRPV4KDM1AMAOAMAOBDAO | |
| SCHEMBL132198 | 0.75 | TRPV4 (0.52) | TRPV4KDM1AMAOAMAOBDAO | |
| SCHEMBL91511 | 0.75 | TRPV4 (0.52) | TRPV4KDM1AMAOAMAOBDAO | |
| SCHEMBL129948 | 0.75 | TRPV4 (0.52) | TRPV4KDM1AMAOAMAOBDAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017198812-A2 | PROCESS FOR THE MANUFACTURE OF 2-SUBSTITUTED-5-(1-METHYLTHIO)ALKYLPYRIDINES | SOLVAY SA (BE) | 2017-11-23 | — | — | WO | disclosed |