Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYCR1 | P32322 | 2/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.42 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.42 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.41 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.41 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HBB | P68871 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30093198 | 0.83 | PYCR1 (0.67) | PYCR1TAAR1AOC3LMNAKDM4E | |
| SCHEMBL3191532 | 0.83 | PYCR1 (0.67) | PYCR1TAAR1AOC3LMNAKDM4E | |
| SCHEMBL14373882 | 0.82 | PYCR1 (0.53) | PYCR1SIGMAR1MAPTCARM1PRMT6 | |
| SCHEMBL15308539 | 0.82 | PYCR1 (0.56) | PYCR1TAAR1AOC3SIGMAR1ACKR3 | |
| SCHEMBL13889677 | 0.82 | TAAR1 (0.61) | PYCR1TAAR1AOC3SIGMAR1ACKR3 | |
| SCHEMBL995037 | 0.81 | TAAR1 (0.43) | PYCR1TAAR1AOC3MAPTLMNA | |
| SCHEMBL23615993 | 0.80 | CARM1 (0.66) | PYCR1TAAR1AOC3SIGMAR1ACKR3 | |
| SCHEMBL308737 | 0.80 | KDM4E (0.62) | PYCR1TAAR1SIGMAR1MAPTTMEM97 | |
| Hydrochloric Acid SCHEMBL5025947 | 0.80 | PYCR1 (0.52) | PYCR1SIGMAR1MAPTCARM1PRMT6 | |
| SCHEMBL9826270 | 0.80 | PYCR1 (0.55) | PYCR1TAAR1AOC3SIGMAR1ACKR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017198785-A1 | OXIME DERIVATIVES USEFUL AS INHIBITORS OF HISTONE DEMETHYLASE KDM4C | IEO - ISTITUTO EUROPEO DI ONCOLOGIA S.R.L. (IT) | 2017-11-23 | — | — | WO | disclosed |