Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 16/20 | 0.66 |
| ▸ | DDB1 | Q16531 | 10/20 | 0.66 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | IKZF3 | Q9UKT9 | 3/20 | 0.45 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.39 |
| ▸ | IL1B | P01584 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19709449 | 0.89 | CRBN (0.52) | CRBNDDB1BRD4IKZF3STAT3 | |
| SCHEMBL22507965 | 0.87 | CRBN (0.58) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL19308879 | 0.87 | CRBN (0.54) | CRBNDDB1BRD4IKZF3STAT3 | |
| SCHEMBL19387868 | 0.85 | CRBN (0.53) | CRBNDDB1BRD4STAT3HDAC3 | |
| SCHEMBL22606726 | 0.84 | CRBN (0.47) | CRBNDDB1BRD4IKZF3ALDH1A1 | |
| SCHEMBL20759891 | 0.84 | CRBN (0.44) | CRBNDDB1BRD4IKZF3ALDH1A1 | |
| SCHEMBL18493738 | 0.84 | CRBN (0.66) | CRBNDDB1BRD4IKZF3ALDH1A1 | |
| SCHEMBL19068590 | 0.83 | CRBN (0.56) | CRBNDDB1BRD4STAT3HDAC3 | |
| SCHEMBL23015941 | 0.82 | CRBN (0.56) | CRBNDDB1BRD4STAT3HDAC3 | |
| SCHEMBL22507992 | 0.82 | CRBN (0.56) | CRBNDDB1BRD4STAT3HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11311609-B2 | Regulating chimeric antigen receptors | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2022-04-26 | — | — | US | disclosed |
| WO-2020132566-A1 | STING PYRAZOLE AGONISTS AND USES THEREOF | NIMBUS TITAN, INC. (US) | 2020-06-25 | — | — | WO | disclosed |
| US-9821068-B2 | Methods to induce targeted protein degradation through bifunctional molecules | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2017-11-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11311609-B2 | Regulating chimeric antigen receptors | NFATC1, TNFRSF9, IL2RA | CRBN 154/4885DDB1 979/4885BRD4 3626/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.