Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 13/20 | 0.52 |
| ▸ | DDB1 | Q16531 | 8/20 | 0.52 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | STAT3 | P40763 | 2/20 | 0.42 |
| ▸ | IKZF3 | Q9UKT9 | 3/20 | 0.41 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.38 |
| ▸ | CCNK | O75909 | 1/20 | 0.38 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | CDK9 | P50750 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19618073 | 0.89 | CRBN (0.66) | CRBNDDB1BRD4STAT3IKZF3 | |
| SCHEMBL22507965 | 0.84 | CRBN (0.58) | CRBNDDB1IKZF3HDAC3HDAC1 | |
| SCHEMBL23945771 | 0.83 | CRBN (0.46) | CRBNDDB1BRD4STAT3IKZF3 | |
| SCHEMBL21341140 | 0.82 | CRBN (0.44) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| SCHEMBL30241739 | 0.82 | CRBN (0.52) | CRBNDDB1STAT3IKZF3CCNK | |
| SCHEMBL26148008 | 0.82 | CRBN (0.52) | CRBNDDB1STAT3IKZF3CCNK | |
| SCHEMBL20759891 | 0.81 | CRBN (0.44) | CRBNDDB1BRD4IKZF3ALDH1A1 | |
| SCHEMBL22606726 | 0.81 | CRBN (0.47) | CRBNDDB1BRD4IKZF3ALDH1A1 | |
| SCHEMBL22959649 | 0.81 | CRBN (0.51) | CRBNDDB1BRD4STAT3IKZF3 | |
| SCHEMBL24818018 | 0.81 | CRBN (0.48) | CRBNDDB1STAT3IKZF3MAP1LC3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017212329-A1 | CLIPTAC COMPOSITION | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2017-12-14 | — | — | WO | disclosed |