Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21719609 | 0.94 | HCAR2 (0.35) | HCAR2LMNAMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL19779338 | 0.94 | HCAR2 (0.35) | HCAR2LMNAMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL20049883 | 0.94 | HCAR2 (0.35) | HCAR2LMNAMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL20049986 | 0.76 | CYP1A2 (0.38) | HCAR2LMNAMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL21718612 | 0.76 | CYP1A2 (0.38) | HCAR2LMNAMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL23583949 | 0.76 | CYP1A2 (0.38) | HCAR2LMNAMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL21720041 | 0.75 | CNR2 (0.32) | HCAR2LMNAMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL21719791 | 0.75 | CNR2 (0.32) | HCAR2LMNAMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL21719757 | 0.75 | CNR2 (0.32) | HCAR2LMNAMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL21719755 | 0.73 | GPR84 (0.36) | HCAR2MAPTCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9822131-B2 | Certain chemical entities, compositions and methods | INTELLIKINE LLC (US) | 2017-11-21 | — | — | US | disclosed |