SCHEMBL19618397

SCHEMBL19618397

c1ccc(-c2cccc(-c3ccc4nc(-c5cccc(-c6ccccc6)c5)cc(-c5ccc(-c6ccnc7ccccc67)cc5)c4c3)c2)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIK3CA P42336 2/20 0.64
ACVR1 Q04771 6/20 0.54
ACACA Q13085 4/20 0.50
MAPK1 P28482 2/20 0.45
KDM4E B2RXH2 2/20 0.45
ALDH1A1 P00352 2/20 0.45
MAPT P10636 2/20 0.45
MEN1 O00255 1/20 0.45
LMNA P02545 1/20 0.45
RECQL P46063 1/20 0.45
KMT2A Q03164 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
CAMKK1 Q8N5S9 1/20 0.45
CAMKK2 Q96RR4 1/20 0.45
ESR1 P03372 1/20 0.44
ESR2 Q92731 1/20 0.44
TOP1 P11387 3/20 0.43
HPGD P15428 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19618468 0.97 PIK3CA (0.60) PIK3CAACVR1ACACAMAPK1KDM4E
SCHEMBL19618327 0.95 PIK3CA (0.60) PIK3CAACVR1ACACAMAPK1KDM4E
SCHEMBL19618346 0.95 PIK3CA (0.60) PIK3CAACVR1ACACAMAPK1KDM4E
SCHEMBL19618305 0.95 PIK3CA (0.68) PIK3CAACVR1ACACAMAPK1KDM4E
SCHEMBL19618388 0.95 PIK3CA (0.68) PIK3CAACVR1ACACAMAPK1KDM4E
SCHEMBL19618285 0.90 PIK3CA (0.52) PIK3CAACVR1ACACAMEN1KMT2A
SCHEMBL19618423 0.89 PIK3CA (0.51) PIK3CAACVR1ACACAMAPK1CAMKK1
SCHEMBL19618279 0.88 PIK3CA (0.56) PIK3CAACVR1ACACAMAPK1KDM4E
SCHEMBL18503951 0.86 ACACA (0.63) ACACAMAPK1KDM4EALDH1A1MAPT
SCHEMBL17343433 0.85 PIK3CA (0.50) PIK3CAACVR1ACACAMAPK1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9825242-B2 Compound for organic optoelectric device, organic light-emitting diode including same, display device including organic light-emitting diode CHEIL INDUSTRIES, INC. (KR) 2017-11-21 US disclosed
US-9825242-B2 Compound for organic optoelectric device, organic light-emitting diode including same, display device including organic light-emitting diode CHEIL INDUSTRIES, INC. (KR) 2017-11-21 US disclosed