SCHEMBL19618601

SCHEMBL19618601

c1ccc(-c2cc(-c3ccccc3)nc(-c3ccc(-c4cc(-c5ccc6ccccc6c5)nc5ccc(-c6cc7ccccc7c7ccccc67)cc45)cc3)n2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A1 P04798 1/20 0.49
CYP1B1 Q16678 1/20 0.49
ACACA Q13085 4/20 0.47
AURKA O14965 1/20 0.45
AURKB Q96GD4 1/20 0.45
ALDH1A1 P00352 5/20 0.44
MAPT P10636 4/20 0.44
HPGD P15428 4/20 0.44
KDM4E B2RXH2 3/20 0.44
ELANE P08246 1/20 0.44
MEN1 O00255 5/20 0.43
KMT2A Q03164 5/20 0.43
LMNA P02545 2/20 0.43
MAPK1 P28482 1/20 0.43
RECQL P46063 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
ESR1 P03372 1/20 0.43
ESR2 Q92731 1/20 0.43
NTSR1 P30989 1/20 0.42
CYP1A2 P05177 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19618596 1.00 CYP1A1 (0.49) CYP1A1CYP1B1ACACAAURKAAURKB
SCHEMBL19618598 0.96 CYP1A1 (0.48) CYP1A1CYP1B1ACACAAURKAAURKB
SCHEMBL19618600 0.96 ACACA (0.45) CYP1A1CYP1B1ACACAAURKAAURKB
SCHEMBL19618599 0.94 CYP1A1 (0.48) CYP1A1CYP1B1ACACAAURKAAURKB
SCHEMBL19618604 0.91 CYP1A1 (0.42) CYP1A1CYP1B1ACACAAURKAAURKB
SCHEMBL19618455 0.91 ACACA (0.47) ACACAAURKAAURKBALDH1A1MAPT
SCHEMBL19618450 0.91 ACACA (0.47) ACACAAURKAAURKBALDH1A1MAPT
SCHEMBL19618321 0.91 CYP1A1 (0.55) CYP1A1CYP1B1ACACAAURKAAURKB
SCHEMBL19618312 0.91 CYP1A1 (0.55) CYP1A1CYP1B1ACACAAURKAAURKB
SCHEMBL19618602 0.90 ACACA (0.47) CYP1A1CYP1B1ACACAAURKAAURKB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9825242-B2 Compound for organic optoelectric device, organic light-emitting diode including same, display device including organic light-emitting diode CHEIL INDUSTRIES, INC. (KR) 2017-11-21 US disclosed
US-9825242-B2 Compound for organic optoelectric device, organic light-emitting diode including same, display device including organic light-emitting diode CHEIL INDUSTRIES, INC. (KR) 2017-11-21 US disclosed