Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.51 |
| ▸ | CCR3 | P51677 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | MC4R | P32245 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12589184 | 0.88 | OPRL1 (0.58) | OPRL1POLBCYP2D6CCR3CYP3A4 | |
| SCHEMBL9174263 | 0.80 | OPRL1 (0.51) | OPRL1POLBCYP2D6CCR3CYP3A4 | |
| SCHEMBL12555766 | 0.79 | OPRL1 (0.54) | OPRL1POLBCYP2D6CCR3CYP3A4 | |
| SCHEMBL10345184 | 0.78 | OPRL1 (0.56) | OPRL1POLBCYP2D6CCR3CYP3A4 | |
| SCHEMBL1990088 | 0.77 | OPRL1 (0.63) | OPRL1POLBCYP2D6CCR3CYP3A4 | |
| Bromide SCHEMBL10345274 | 0.77 | OPRL1 (0.55) | OPRL1POLBCYP2D6CCR3CYP3A4 | |
| SCHEMBL6749277 | 0.76 | OPRL1 (0.61) | OPRL1POLBCYP2D6CCR3SIGMAR1 | |
| SCHEMBL28737516 | 0.76 | TSHR (0.54) | OPRL1POLBCYP2D6CCR3CYP3A4 | |
| SCHEMBL10345569 | 0.76 | CHRM2 (0.58) | OPRL1POLBCYP2D6CCR3CYP3A4 | |
| SCHEMBL7406058 | 0.76 | OPRL1 (0.65) | OPRL1POLBCYP2D6CCR3CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9820971-B2 | Anesthetic compounds and related methods of use | THE GENERAL HOSPITAL CORPORATION (US) | 2017-11-21 | — | — | US | disclosed |