Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CCR3 | P51677 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12589184 | 0.91 | OPRL1 (0.58) | OPRL1CYP2D6CYP3A4TSHRALDH1A1 | |
| SCHEMBL10345158 | 0.84 | CYP3A4 (0.50) | OPRL1CYP2D6CYP3A4TSHRALDH1A1 | |
| SCHEMBL10345149 | 0.84 | CHRM2 (0.53) | OPRL1CYP2D6CYP3A4ALDH1A1POLB | |
| SCHEMBL25600026 | 0.83 | OPRL1 (0.55) | OPRL1CYP2D6CYP3A4TSHRALDH1A1 | |
| SCHEMBL19322400 | 0.81 | OPRL1 (0.53) | OPRL1CYP2D6CYP3A4TSHRALDH1A1 | |
| Acetic Acid SCHEMBL10974566 | 0.80 | CHRM2 (0.54) | CYP2D6CYP3A4TSHRALDH1A1KDM4E | |
| SCHEMBL4511014 | 0.80 | OPRL1 (0.55) | OPRL1CYP2D6CYP3A4TSHRALDH1A1 | |
| SCHEMBL19618751 | 0.80 | OPRL1 (0.52) | OPRL1CYP2D6CYP3A4TSHRALDH1A1 | |
| SCHEMBL4502776 | 0.80 | POLB (0.52) | CYP2D6CYP3A4TSHRALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL9179035 | 0.79 | POLB (0.54) | OPRL1CYP2D6CYP3A4TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5453422-A | Animal growth promoters | BAYER AKTIENGESELLSCHAFT (DE) | 1995-09-26 | — | — | US | disclosed |
| US-5284842-A | Active against gramnegative bacteria | BAYER AKTIENGESELLSCHAFT (DE) | 1994-02-08 | — | — | US | disclosed |
| US-5173484-A | Animal growth regulators | BAYER AKTIENGESELLSCHAFT (DE) | 1992-12-22 | — | — | US | disclosed |
| EP-0326916-A2 | Quinolone- and naphthyridone-carboxylic acid derivatives, method for their preparation and antibacterial agents and food additives containing them | BAYER AG (DE) | 1989-08-09 | — | — | EP | disclosed |