Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPA1 | P15085 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27389541 | 0.81 | CPA1 (0.53) | CPA1 | |
| SCHEMBL27692711 | 0.81 | CPA1 (0.45) | CPA1 | |
| SCHEMBL29034485 | 0.81 | ALPI (0.56) | CPA1 | |
| SCHEMBL27623586 | 0.81 | CPA1 (0.47) | CPA1 | |
| SCHEMBL2800996 | 0.81 | ALPI (0.56) | CPA1 | |
| SCHEMBL15635730 | 0.79 | CPA1 (0.54) | CPA1 | |
| SCHEMBL20506887 | 0.78 | CPA1 (0.45) | CPA1 | |
| SCHEMBL517463 | 0.78 | ALDH1A1 (0.60) | HPGDCYP3A4TSHRNPC1RAB9A | |
| SCHEMBL2600694 | 0.78 | ALDH1A1 (0.60) | HPGDCYP3A4TSHRNPC1RAB9A | |
| SCHEMBL17761604 | 0.78 | ALDH1A1 (0.60) | HPGDCYP3A4TSHRNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3458042-A1 | CARBOXYLIC ACIDS FOR TREATING/PREVENTING A SKIN DISEASE | Proponent Biotech GmbH (CH) | 2019-03-27 | — | — | EP | disclosed |
| WO-2017198701-A1 | CARBOXYLIC ACIDS FOR TREATING/PREVENTING A SKIN DISEASE | PROPONENT BIOTECH GMBH (CH) | 2017-11-23 | — | — | WO | disclosed |
| CN-100376242-C | 2-aryl-propionic acid and medicine composition containing same | DOMPAY CO LTD (IT) | 2008-03-26 | — | — | CN | disclosed |
| CN-1612729-A | 2-Aryl-propionic acids and pharmaceutical compositions containing them | DOMPAY CO LTD (IT) | 2005-05-04 | — | — | CN | disclosed |