Fondaparinux

SCHEMBL19619397

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nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

SERPINC1

The experimentally established mechanism targets of Fondaparinux. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

	gene	UniProt	supporting neighbours	confidence
▸	SERPINC1 known ✓	P01008	2/20	0.49

▸	F10	P00742	4/20	1.00

▸	F2	P00734	1/20	0.49

▸	BDNF	P23560	3/20	0.47

▸	PTN	P21246	2/20	0.47

▸	MDK	P21741	2/20	0.47

▸	HPSE	Q9Y251	9/20	0.46

▸	PF4	P02776	2/20	0.45

▸	FGF1	P05230	1/20	0.44

▸	IFNG	P01579	1/20	0.42

▸	BMP2	P12643	1/20	0.42

▸	CCL2	P13500	1/20	0.42

▸	VEGFA	P15692	1/20	0.42

▸	SELP	P16109	1/20	0.42

▸	BMP6	P22004	1/20	0.42

▸	CXCL12	P48061	1/20	0.42

▸	CCL11	P51671	1/20	0.42

▸	WNT3A	P56704	1/20	0.42

▸	SELPLG	Q14242	1/20	0.42

▸	SHH	Q15465	1/20	0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Fondaparinux SCHEMBL15296579	1.00	F10 (1.00)	F10SERPINC1F2BDNFPTN
Fondaparinux SCHEMBL14227800	1.00	F10 (1.00)	F10SERPINC1F2BDNFPTN
Fondaparinux SCHEMBL1650579	1.00	F10 (1.00)	F10SERPINC1F2BDNFPTN
Fondaparinux SCHEMBL17655218	1.00	F10 (1.00)	F10SERPINC1F2BDNFPTN
SCHEMBL13795898	0.92	F10 (0.85)	F10SERPINC1F2BDNFPTN
SCHEMBL10148985	0.92	F10 (0.85)	F10SERPINC1F2BDNFPTN
SCHEMBL13130300	0.92	F10 (0.84)	F10SERPINC1F2BDNFPTN
SCHEMBL15199336	0.90	F10 (0.81)	F10SERPINC1F2BDNFPTN
SCHEMBL18883211	0.90	F10 (0.81)	F10SERPINC1F2BDNFPTN
SCHEMBL10157440	0.90	F10 (0.81)	F10SERPINC1F2BDNFPTN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-9822140-B2	Methods and intermediates for the preparation of fondaparinux	ACADEMIA SINICA (TW)	2017-11-21	—	—	US	disclosed