SCHEMBL10148985

SCHEMBL10148985

CO[C@H]1OC(COS(=O)(=O)O)[C@@H](O[C@@H]2OC(C(=O)O)[C@H](O[C@@H]3OC(COS(=O)(=O)O)[C@@H](O[C@@H]4OC(C(=O)O)[C@@H](O[C@H]5OC(COS(=O)(=O)O)[C@@H](O)[C@H](O)C5NS(=O)(=O)O)[C@H](O)C4O)[C@@H](OSOOO)C3NS(=O)(=O)O)[C@@H](O)C2OS(=O)(=O)O)[C@H](O)C1NS(=O)(=O)O

nearest known ligand 0.85

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F10 P00742 4/20 0.85
SERPINC1 P01008 2/20 0.45
F2 P00734 1/20 0.45
BDNF P23560 3/20 0.43
PTN P21246 2/20 0.43
MDK P21741 2/20 0.43
HPSE Q9Y251 9/20 0.41
PF4 P02776 2/20 0.40
FGF1 P05230 1/20 0.39
IFNG P01579 1/20 0.38
BMP2 P12643 1/20 0.38
CCL2 P13500 1/20 0.38
VEGFA P15692 1/20 0.38
SELP P16109 1/20 0.38
BMP6 P22004 1/20 0.38
CXCL12 P48061 1/20 0.38
CCL11 P51671 1/20 0.38
WNT3A P56704 1/20 0.38
SELPLG Q14242 1/20 0.38
SHH Q15465 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13795898 1.00 F10 (0.85) F10SERPINC1F2BDNFPTN
Fondaparinux SCHEMBL14227800 0.92 F10 (1.00) F10SERPINC1F2BDNFPTN
Fondaparinux SCHEMBL19619397 0.92 F10 (1.00) F10SERPINC1F2BDNFPTN
Fondaparinux SCHEMBL17655218 0.92 F10 (1.00) F10SERPINC1F2BDNFPTN
Fondaparinux SCHEMBL15296579 0.92 F10 (1.00) F10SERPINC1F2BDNFPTN
Fondaparinux SCHEMBL1650579 0.92 F10 (1.00) F10SERPINC1F2BDNFPTN
SCHEMBL14977908 0.89 F10 (0.67) F10SERPINC1F2BDNFPTN
SCHEMBL13130300 0.86 F10 (0.84) F10SERPINC1F2BDNFPTN
SCHEMBL10148982 0.84 F10 (0.62) F10SERPINC1F2BDNFPTN
SCHEMBL13796405 0.84 F10 (0.62) F10SERPINC1F2BDNFPTN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8114970-B2 Synthetic heparin monosaccharides ALCHEMIA LIMITED (AU) 2012-02-14 US disclosed
US-20090187013-A1 SYNTHETIC HEPARIN PENTASACCHARIDES ALCHEMIA LIMITED (AU) 2009-07-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090187013-A1 SYNTHETIC HEPARIN PENTASACCHARIDES HPSE, DDOST, STT3A F10 107/4885SERPINC1 8/4885F2 68/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.