SCHEMBL19619456

SCHEMBL19619456

NCC1CCC(C2CCC(c3ccc(-c4cc(F)c(F)c(F)c4)c(F)c3F)CC2)CC1

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.33
ALOX5AP P20292 6/20 0.33
FEN1 P39748 6/20 0.33
OPRL1 P41146 5/20 0.32
FFAR4 Q5NUL3 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17552980 0.87 DGAT1 (0.33) DGAT1ALOX5APFEN1OPRL1FFAR4
SCHEMBL17356640 0.85 OPRL1 (0.35) DGAT1OPRL1
SCHEMBL17552979 0.83 OPRL1 (0.34) DGAT1OPRL1
SCHEMBL19619453 0.82 ALOX5AP (0.35) ALOX5APFEN1
SCHEMBL17359236 0.82 ALOX5AP (0.33) ALOX5APFEN1
SCHEMBL17356584 0.82 DGAT1 (0.35) DGAT1ALOX5APFEN1OPRL1FFAR4
SCHEMBL17356644 0.82 GAA (0.35) DGAT1OPRL1
SCHEMBL18458901 0.82 HTR2A (0.32) ALOX5APFEN1
SCHEMBL19619449 0.81 ESR2 (0.36) DGAT1FFAR4
SCHEMBL19619455 0.81 DPP4 (0.32) DGAT1ALOX5APFEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9822304-B2 Liquid crystal composition and liquid crystal display element containing the same DIC CORPORATION (JP) 2017-11-21 US disclosed