Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 4/20 | 0.55 |
| ▸ | CA1 | P00915 | 12/20 | 0.46 |
| ▸ | CA2 | P00918 | 12/20 | 0.46 |
| ▸ | CA7 | P43166 | 3/20 | 0.43 |
| ▸ | CA13 | Q8N1Q1 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA6 | P23280 | 2/20 | 0.43 |
| ▸ | CA3 | P07451 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL941570 | 0.84 | MMP2 (0.61) | MMP2CA1CA2CA7CA13 | |
| SCHEMBL940709 | 0.84 | MMP2 (0.54) | MMP2CA1CA2CA7CA13 | |
| SCHEMBL940094 | 0.81 | MMP2 (0.60) | MMP2CA1CA2CA7CA13 | |
| SCHEMBL940201 | 0.81 | MMP2 (0.60) | MMP2CA1CA2CA7CA13 | |
| SCHEMBL939528 | 0.81 | MMP2 (0.66) | MMP2CA1CA2CA7CA13 | |
| SCHEMBL942895 | 0.79 | MMP2 (0.64) | MMP2CA1CA2CA7CA13 | |
| SCHEMBL939843 | 0.78 | MMP2 (0.66) | MMP2CA1CA2CA7CA13 | |
| SCHEMBL7994545 | 0.78 | MMP2 (0.66) | MMP2CA1CA2CA7CA13 | |
| SCHEMBL941037 | 0.78 | MMP2 (0.70) | MMP2CA1CA2CA7CA13 | |
| SCHEMBL939496 | 0.77 | MMP2 (0.61) | MMP2CA1CA2CA7CA13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9822092-B2 | ArylSulfonamide-based matrix metalloprotease inhibitors | NOVARTIS AG (CH) | 2017-11-21 | — | — | US | disclosed |