⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11576921 | 0.76 | — | — | |
| SCHEMBL195475 | 0.74 | GRIK1 (0.42) | — | |
| SCHEMBL680154 | 0.74 | — | — | |
| SCHEMBL16287785 | 0.73 | — | — | |
| SCHEMBL3004862 | 0.73 | PPARG (0.43) | — | |
| SCHEMBL3004869 | 0.73 | PPARG (0.43) | — | |
| SCHEMBL12500474 | 0.72 | — | — | |
| SCHEMBL5318104 | 0.72 | — | — | |
| SCHEMBL289814 | 0.72 | — | — | |
| SCHEMBL5847747 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 604 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239786-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT AND PREVENTION OF CANCER | YALE UNIVERSITY | 2024-07-18 | — | — | US | claimed |
| WO-2022221181-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT AND PREVENTION OF CANCER | YALE UNIVERSITY (US) | 2022-10-20 | — | — | WO | claimed |
| US-7479526-B2 | Hydroxy-functional binder components | CYTEC SURFACE SPECIALTIES AUSTRIA GMBH (AT) | 2009-01-20 | — | — | US | claimed |
| US-20060194922-A1 | Hydroxy-functional binder components | CYTEC SURFACE SPECIALTIES AUSTRIA GMBH (AT) | 2006-08-31 | — | — | US | claimed |
| US-20240239786-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT AND PREVENTION OF CANCER | YALE UNIVERSITY | 2024-07-18 | — | — | US | disclosed |
| EP-4373493-A1 | BIFUNCTIONAL COMPOUNDS FOR DEGRADING BTK WITH ENHANCED IMID ACTIVITY | Nurix Therapeutics, Inc. (US) | 2024-05-29 | — | — | EP | disclosed |
| EP-4370123-A1 | BIFUNCTIONAL COMPOUNDS FOR DEGRADING BTK WITH DIMINISHED IMID ACTIVITY | Nurix Therapeutics, Inc. (US) | 2024-05-22 | — | — | EP | disclosed |
| WO-2024086296-A1 | COMPOUNDS USEFUL IN MODULATING EGFR AND PI3K | MEKANISTIC THERAPEUTICS LLC (US) | 2024-04-25 | — | — | WO | disclosed |
| US-20240124475-A1 | BIFUNCTIONAL COMPOUNDS FOR DEGRADING BTK VIA UBIQUITIN PROTEOSOME PATHWAY | NURIX THERAPEUTICS, INC. | 2024-04-18 | — | — | US | disclosed |
| US-20240092766-A1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | VERTEX PHARMA (US) | 2024-03-21 | — | — | US | disclosed |
| EP-4334303-A1 | COMPOUNDS FOR INHIBITING OR DEGRADING ITK, COMPOSITIONS, COMPRISING THE SAME METHODS OF THEIR MAKING AND METHODS OF THEIR USE | Nurix Therapeutics, Inc. (US) | 2024-03-13 | — | — | EP | disclosed |
| EP-4334302-A1 | COMPOUNDS FOR INHIBITING OR DEGRADING TARGET PROTEINS, COMPOSITIONS, COMPRISING THE SAME, METHODS OF THEIR MAKING, AND METHODS OF THEIR USE | Nurix Therapeutics, Inc. (US) | 2024-03-13 | — | — | EP | disclosed |
| EP-0499434-A1 | Detergent compositions | UNILEVER PLC (GB) | 1992-08-19 | — | — | EP | disclosed |
| EP-0491532-A1 | Detergent compositions | UNILEVER PLC (GB) | 1992-06-24 | — | — | EP | disclosed |
| EP-0491531-A1 | Detergent compositions | UNILEVER PLC (GB) | 1992-06-24 | — | — | EP | disclosed |
| EP-0487262-A2 | Detergent compositions | UNILEVER PLC (GB) | 1992-05-27 | — | — | EP | disclosed |
| US-3991080-A | Prostaglandin intermediates | HOFFMANN-LA ROCHE INC. (US) | 1976-11-09 | — | — | US | disclosed |
| US-3975406-A | Hexahydro-5-oxy-2-loweralkoxy-2H-cyclopenta[b]-furan-4-carbonitrile intermediates for prostaglandins | MAYER HANS JOHANN | 1976-08-17 | — | — | US | disclosed |
| US-3974185-A | Hexahydro-cyclopentano[b]furans having a 2-C.tbd.C containing substituent in the 4-position | HOFFMANN-LA ROCHE INC. (US) | 1976-08-10 | — | — | US | disclosed |
| US-3970674-A | Certain hexahydro-2-loweralkoxy-5-oxycyclopenta [b] furans containing an olefinic substituent in the 4-position | HOFFMANN-LA ROCHE INC. (US) | 1976-07-20 | — | — | US | disclosed |