SCHEMBL19619922

SCHEMBL19619922

C=Nn1nnc2ccccc21

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC9A1 P19634 9/20 0.50
MAPT P10636 2/20 0.50
POLB P06746 1/20 0.50
MAPK1 P28482 1/20 0.50
ATM Q13315 1/20 0.50
KEAP1 Q14145 1/20 0.50
ALDH1A1 P00352 1/20 0.50
CYP1A2 P05177 1/20 0.50
CYP3A4 P08684 1/20 0.50
CYP2D6 P10635 1/20 0.50
CYP2C9 P11712 1/20 0.50
THPO P40225 1/20 0.50
CYP4Z1 Q86W10 1/20 0.50
RAB9A P51151 3/20 0.46
NPC1 O15118 2/20 0.46
TP53 P04637 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
DGAT1 O75907 1/20 0.46
GRM2 Q14416 1/20 0.43
KCNMA1 Q12791 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5694968 0.83 SLC9A1 (0.54) SLC9A1MAPTPOLBMAPK1ATM
SCHEMBL15040780 0.78 SLC9A1 (0.53) SLC9A1MAPTPOLBMAPK1ATM
SCHEMBL1259144 0.76 POLB (0.52) SLC9A1MAPTPOLBMAPK1ATM
SCHEMBL1829869 0.76 POLB (0.52) SLC9A1MAPTPOLBMAPK1ATM
SCHEMBL13604205 0.75 SLC9A1 (0.50) SLC9A1MAPTPOLBMAPK1ATM
SCHEMBL10772822 0.75 SLC9A1 (0.46) SLC9A1MAPTPOLBMAPK1ATM
SCHEMBL13604190 0.73 SLC9A1 (0.44) SLC9A1MAPTPOLBMAPK1ATM
SCHEMBL5694930 0.73 SLC9A1 (0.44) SLC9A1MAPTPOLBMAPK1ATM
SCHEMBL5694929 0.73 SLC9A1 (0.44) SLC9A1MAPTPOLBMAPK1ATM
SCHEMBL28389006 0.72 POLB (0.47) SLC9A1MAPTPOLBMAPK1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3416511-B1 INFRARED-TRANSPARENT POROUS POLYMER TEXTILE FOR HUMAN BODY COOLING AND HEATING UNIV LELAND STANFORD JUNIOR (US) 2022-03-30 EP disclosed
US-11160489-B2 Wireless optofluidic systems for programmable in vivo pharmacology and optogenetics THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2021-11-02 US disclosed
EP-3141918-B1 IMPROVEMENTS IN OR RELATING TO DETERMINING A FAULT LOCATION IN A POWER TRANSMISSION MEDIUM GENERAL ELECTRIC TECHNOLOGY GMBH (CH) 2020-10-28 EP disclosed
US-10617300-B2 Injectable and implantable cellular-scale electronic devices THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2020-04-14 US disclosed
US-10333069-B2 Purification of carbon nanotubes via selective heating THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2019-06-25 US disclosed
US-20190090801-A1 WIRELESS OPTOFLUIDIC SYSTEMS FOR PROGRAMMABLE IN VIVO PHARMACOLOGY AND OPTOGENETICS WASHINGTON UNIVERSITY IN ST. LOUIS (US) 2019-03-28 US disclosed
US-9825229-B2 Purification of carbon nanotubes via selective heating THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2017-11-21 US disclosed