Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.36 |
| ▸ | PPARD | Q03181 | 3/20 | 0.36 |
| ▸ | PPARA | Q07869 | 3/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | PDE1A | P54750 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 6/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14748446 | 0.89 | PTGDR2 (0.45) | ARPPARDPPARAPDE4BCHRM1 | |
| SCHEMBL19622210 | 0.84 | PDE4B (0.44) | ARPDE4BCHRM1PDE4AADRA1A | |
| SCHEMBL14748461 | 0.84 | TBXA2R (0.36) | ARPPARDPPARAPDE4BCHRM1 | |
| SCHEMBL14748449 | 0.79 | PDE4B (0.38) | ARPDE4BCHRM1PDE4AADRA1A | |
| SCHEMBL8005546 | 0.79 | AR (0.59) | ARPPARDPPARAPDE4BCHRM1 | |
| SCHEMBL14748365 | 0.76 | CYP11B1 (0.49) | ARFFAR1SCN9A | |
| SCHEMBL14748470 | 0.76 | PDE4B (0.40) | ARPDE4BCHRM1PDE4AADRA1A | |
| SCHEMBL8005549 | 0.76 | AR (0.44) | ARPDE4BCHRM1PDE4AADRA1A | |
| SCHEMBL14470676 | 0.75 | PDE4B (0.53) | PDE4BCHRM1PDE4AADRA1APDE1A | |
| SCHEMBL7997146 | 0.74 | PTGDR2 (0.42) | PPARDPPARAPTGDR2FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3246034-A1 | BORON-CONTAINING SMALL MOLECULES AS ANTI-INFLAMMATORY AGENTS | Anacor Pharmaceuticals, Inc. (US) | 2017-11-22 | — | — | EP | disclosed |