Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.42 |
| ▸ | PPARD | Q03181 | 9/20 | 0.39 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.38 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.37 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14748446 | 0.84 | PTGDR2 (0.45) | PTGDR2PPARDFFAR1PPARA | |
| SCHEMBL19622171 | 0.81 | TSHR (0.54) | PPARDKDM4EPPARGALOX15TSHR | |
| SCHEMBL14748434 | 0.75 | PDE4A (0.50) | — | |
| SCHEMBL19622265 | 0.74 | AR (0.36) | PTGDR2PPARDFFAR1PPARA | |
| SCHEMBL14748461 | 0.74 | TBXA2R (0.36) | PPARDPPARA | |
| SCHEMBL320418 | 0.72 | PTGDR2 (0.66) | PTGDR2FFAR1KDM4ETSHR | |
| SCHEMBL8006259 | 0.71 | TTR (0.57) | KDM4E | |
| SCHEMBL14748412 | 0.70 | PDE4B (0.41) | KDM4E | |
| SCHEMBL14748410 | 0.70 | ALDH1A1 (0.54) | TSHR | |
| SCHEMBL24240486 | 0.69 | CYP1A2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009111676-A2 | BORON-CONTAINING SMALL MOLECULES AS ANTI-INFLAMMATORY AGENTS | ANACOR PHARMACEUTICALS, INC (US) | 2009-09-11 | — | — | WO | disclosed |