Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 11/20 | 0.72 |
| ▸ | MLNR | O43193 | 4/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2716077 | 0.84 | EPHX2 (1.00) | EPHX2 | |
| SCHEMBL16422849 | 0.82 | KMT2A (0.51) | EPHX2MLNRCYP3A4MAPTKDM4E | |
| SCHEMBL7470380 | 0.81 | KMT2A (0.50) | EPHX2MLNRCYP3A4MAPTKDM4E | |
| SCHEMBL1704119 | 0.80 | MLNR (0.70) | EPHX2MLNRCYP3A4ALDH1A1 | |
| SCHEMBL1704864 | 0.78 | MLNR (0.68) | EPHX2MLNRCYP3A4 | |
| SCHEMBL1703969 | 0.77 | MLNR (0.63) | EPHX2MLNRCYP3A4MAPTALDH1A1 | |
| SCHEMBL27904819 | 0.77 | MLNR (0.66) | MLNRCYP3A4KDM4EALDH1A1GAA | |
| SCHEMBL377801 | 0.77 | ALDH1A1 (0.75) | MAPTKDM4EALDH1A1GAA | |
| SCHEMBL3327432 | 0.77 | ALDH1A1 (0.46) | EPHX2MLNRCYP3A4MAPTKDM4E | |
| SCHEMBL3327437 | 0.77 | ALDH1A1 (0.46) | EPHX2MLNRCYP3A4MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2528604-B1 | ACYL PIPERIDINE INHIBITORS OF SOLUBLE EPOXIDE HYDROLASE | UNIV CALIFORNIA (US) | 2017-11-22 | — | — | EP | disclosed |